Journal of Radioanalytical and Nuclear Chemistry

, Volume 173, Issue 1, pp 185–193 | Cite as

Technetium-99m generator based on 12-molybdocerate —99Mo precipitate as column matrix

  • M. A. El Absy
  • I. M. El Naggar
  • A. I. Audah


The preparation of insoluble 12-molybdocerate(IV) from99Mo of low specific activity, produced by thermal neutron irradiation of MoO3, is described. Samples of the material are dried at 50, 100 and 200°C and used as column matrices from which the generated99mTc activity is periodically eluted with saline solution or saline solution containing 5·10−5M K2CrO4 as an oxidant. The elution yields of99mTc are high and reproducible (95–81%) with radionuclidic purity ≥99.98%. Both chemical and radiochemical purity (as TcO 4 ) of the eluates decrease with increasing drying temperature of the column matrix. Using chromated saline solution as eluent improves the radiochemical purity of the99mTc eluate.


Physical Chemistry Chromated Inorganic Chemistry Saline Solution MoO3 
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  1. 1.
    Radiopharmaceuticals from Generator-Produced Radionuclides, Panel Proc. Series STI/PUB/294, Vienna, IAEA, 1971.Google Scholar
  2. 2.
    W. C. ECKELMAN, B. M. COURSAY, Int. J. Appl. Radiation Isotopes, 33, (1982) 10.Google Scholar
  3. 3.
    K. KRISTENSEN, Preparation and Control of Radiopharmaceuticals in Hospitals, Technical Report Series STI/DOC/10/194, Vienna, IAEA 1979.Google Scholar
  4. 4.
    V. I. SPITSYN N. B. MIKHEEV, At. Energy Rev., 9 (1971) 827.Google Scholar
  5. 5.
    R. E. BOYD, Radiochim. Acta, 30 (1982) 123.Google Scholar
  6. 6.
    V. J. MOLINSKI, Int. J. Appl. Radiation Isotopes, 33 (1982) 811.CrossRefGoogle Scholar
  7. 7.
    H. ARINO, H. H. KRAMER, Int. J. Appl. Radiation Isotopes, 26 (1975) 301.CrossRefGoogle Scholar
  8. 8.
    R. MÜNZE, O. HLADIK, G. BERNHARD, W. BOESSERT, R. SCHWARZBACH, Int. J. Appl. Radiation Isotopes, 35 (1984) 749.CrossRefGoogle Scholar
  9. 9.
    S. A. ALI, H. J. ACHE, Radiochim. Acta, 41 (1987) 65.Google Scholar
  10. 10.
    M. A. EL-ABSY, Radiochim. Acta, 55 (1991) 23.Google Scholar
  11. 11.
    N. B. MIKHEEV, M. EL-GARHY, Z. MOUSTAFA, Atompraxis, 10 (1964) 263.Google Scholar
  12. 12.
    M. EL-GARHY, Z. MOUSTAFA, N. B. MIKHEEV, Atompraxis, 12 (1966) 93.Google Scholar
  13. 13.
    J. V. EVANS, P. W. MOORE, M. E. SHYING, J. M. SODEAU, Proc. World Congress on Nuclear Medicine and Biology, Vol. 2, Paris, 1982, p. 1592.Google Scholar
  14. 14.
    D. V. S. NARASIMHAN, P. VANAJA, R. S. MANI, J. Radioanal. Nucl. Chem., 85 (1984) 163.Google Scholar
  15. 15.
    J. V. EVANS, P. W. MOORE, M. E. SHYING, J. M. SODEAU, Int. J. Appl. Radiation Isotopes, 38 (1987) 19.CrossRefGoogle Scholar
  16. 16.
    M. A. EL-ABSY, S. EL-BAYOUMY, Isotopenpraxis, 26 (1990) 60.Google Scholar
  17. 17.
    F. A. COTTON, G. WILKINSON, Advanced Inorganic Chemistry, A Comprehensive Text, Wiley Eastern Limited, New Delhi, 3rd ed., 1979.Google Scholar
  18. 18.
    S. A. COTTON, F. A. HART, The Heavy Transition Elements, The Macmillan Press, Ltd, London and Basingstoke, 1975.Google Scholar
  19. 19.
    K. SVOBODA, J. LEZAMA, J. TENDILLA, F. MELICHAR, M. TYMPL, J. Radioanal. Nucl. Chem., 96 (1985) 405.Google Scholar
  20. 20.
    E. B. SANDELL, Colorimetric Determination of Traces of Metals, Interscience Publishers, Inc., New York 1959.Google Scholar
  21. 21.
    H. S. STERN, I. ZOLLE, J. G. McFREE, Int. J. Appl. Radiation Isotopes, 16 (1965) 283.CrossRefGoogle Scholar
  22. 22.
    N. RAMAMOORTHY, P. VANAJA, S. P. IYER, R. S. MANI, Seminar on Radionuclide Generator Technology, IAEA-Sr-131/23 Vienna, Austria, 13–17 October 1986.Google Scholar

Copyright information

© Akadémiai Kiadó 1993

Authors and Affiliations

  • M. A. El Absy
    • 1
  • I. M. El Naggar
    • 2
  • A. I. Audah
    • 1
  1. 1.Radioisotope Production DepartmentCairoEgypt
  2. 2.Nuclear Chemistry Department, Nuclear Research CentreAtomic Energy EstablishmentCairoEgypt

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