Journal of Molecular Evolution

, Volume 26, Issue 4, pp 341–346 | Cite as

Archetypical features in tRNA families

  • Krikor Nicoghosian
  • Michel Bigras
  • David Sankoff
  • Robert Cedergren


A compilation of known tRNA, and tRNA gene sequences from archaebacteria, eubacteria, and eukaryotes permits the construction of tRNA cloverleafs which show conserved structural elements for each tRNA family. Positions conserved across the three kingdoms are thought to represent archetypical features of tRNAs which preceded the divergence of these kingdoms.

Key words

Evolution tRNA Recognition sites Statistics 


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Copyright information

© Springer-Verlag New York Inc. 1987

Authors and Affiliations

  • Krikor Nicoghosian
    • 1
  • Michel Bigras
    • 2
  • David Sankoff
    • 3
  • Robert Cedergren
    • 1
  1. 1.Département de BiochimieUniversité de MontréalMontréalCanada
  2. 2.Département d'Informatique et Recherche OpérationnelleUniversité de MontréalMontréalCanada
  3. 3.Centre de Recherches MathématiquesUniversité de MontréalMontréalCanada

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