Summary
The protein keratin can induce a reversible change in morphology of some granular strains ofTrichophyton mentagrophytes leading to a gross appearance which is indistinguishable from the pleomorphic mutation. The only other chemical which induced the same morphological change was a low concentration of sodium acetate. Pleomorphic cultures ofT. mentagrophytes were unaffected.
Similar content being viewed by others
Literature
Cochrane, V. W. (1958) Physiology of Fungi. New York, John Wiley and Sons, Inc.
Chattaway, F. W., Ellis, D. A. &Barlow, A. J. E. (1963) Peptidases of dermatophytes. J. invest. Derm.41 31–37
Hejtmánková-Uhrová, N. (1960) Interessante Chemomorphose beiTrichophyton gypseum Bodin 1902. Naturwissenschaften47 309.
Klein, D. T. (1963) Morphological response ofTrichophyton mentagrophytes to methionine. J. gen. Microbiol.31 91–96.
Klein, D. T. (1964a) Interrelation of pH, temperature, and growth in the induction of pleomorphism inTrichophyton mentagrophytes. Mycologia56 656–661.
Klein, D. T. (1964b) Time-temperature interaction in the induction of pleomorphism inTrichophyton mentagrophytes. J. gen. Microbiol.34 125–130.
Sabouraud, R. (1910) Les Teignes. Paris, Masson et Cie.
Tatum, E. L., Barratt, R. W. &Cutter, V. M. (1949) Chemical induction of colonial paramorphs inNeurospora andSyncephalastrum. Science109 509–511.
Weitzman, I., (1964) Variation inMicrosporum gypseum. I. A genetic study of pleomorphism. Sabouraudia3 195–204.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Klein, D.T. Morphological response of Trichophyton mentagrophytes to keratin. Mycopathologia et Mycologia Applicata 26, 111–116 (1965). https://doi.org/10.1007/BF02098596
Issue Date:
DOI: https://doi.org/10.1007/BF02098596