Antonie van Leeuwenhoek

, Volume 32, Issue 1, pp 171–182 | Cite as

Bacteriocin production by members of the genusKlebsiella

  • A. H. Stouthamer
  • G. A. Tieze
Article

Abstract

Bacteriocin production was tested in 36Klebsiella and 3Enterobacter aerogenes strains. Bacteriocins produced byK. pneumoniae were found to be active on most strains ofK. edwardsi, K. aerogenes, K. rhinoscleromatis andE. aerogenes. The bacteriocin produced byE. aerogenes 37 is also active onK. pneumoniae andK. ozaenae. The bacteriocins produced byK. rhinoscleromatis, K. edwardsi andK. aerogenes are active on only a few strains. The activity spectra of the bacteriocins of a number of strains were similar. The method of classification used for colicins could not be applied to these bacteriocins as mutants resistant to one bacteriocin were nearly always resistant to all other bacteriocins. One mutant, though resistant, still adsorbed the bacteriocin to which it was resistant and it is very likely that the same applies for all other resistant mutants. The hypothesis is made that allKlebsiella bacteriocins have the same biochemical target, or more likely, possess a common transmission mechanism.

Keywords

Resistant Mutant Activity Spectrum Transmission Mechanism Bacteriocin Production 3Enterobacter Aerogenes 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Adams, M. 1959. Bacteriophages. Interscience Publishers, New York.Google Scholar
  2. Cowan, S. T., Steel, K. J., Shaw, C. andDuguid, J. P. 1960. A classification of theKlebsiella group. J. Gen. Microbiol.23 601–612.PubMedGoogle Scholar
  3. Fredericq, P. 1948. Actions antibiotiques réciproques chez lesEnterobacteriaceae. Rev. Belge Pathol. Med. Exptl.29 (Suppl. 4), 1–107.Google Scholar
  4. Fredericq, P. 1949. Sur la résistance croisée entre colicine E et bacteriophage III. Compt. Rend.143 1011–1013.Google Scholar
  5. Fredericq, P. 1951. Origine spontanée des mutants deE. coli V produisant la colicine M. Antonie van Leeuwenhoek17 227–231.PubMedGoogle Scholar
  6. Fredericq, P. 1957. Colicins. Ann. Rev. Microbiol.11 7–22.Google Scholar
  7. Fredericq, P. 1963. Colicines et autres bactériocines. Ergeb. Mikrobiol. Immunol. Exp. Therap. Berlin37 114–161.Google Scholar
  8. Fredericq, P. etGratia, A. 1950. Rapports entre colicines et bactériophages du groupe T.1–T.7. Antonie van Leeuwenhoek16 119–121.PubMedGoogle Scholar
  9. Hamon, Y. 1964. Les bactériocines. Ann. Inst. Pasteur107 Suppl. novembre, 18–53.Google Scholar
  10. Hamon, Y. etPéron, Y. 1963. Individualisation de quelques nouvelles familles d'entérobactériocines. Compt. Rend.257 309–311.Google Scholar
  11. Hormaeche, E. andEdwards, P. R. 1960. A proposed genusEnterobacter. Intern. Bull. Bacteriol. Nomen. Tax.10 71.Google Scholar
  12. Ivánovics, G. 1962. Bacteriocins and bacteriocin-like substances. Bacteriol. Rev.26 108–118.Google Scholar
  13. Jacob, F., Siminovitch, L. etWollman, E. 1952. Sur la biosynthèse d'une colicine et sur son mode d'action. Ann. Inst. Pasteur83 295–315.Google Scholar
  14. Jacob, F., Lwoff, A., Siminovitch, A. etWollman, E. 1953. Définition de quelques termes relatifs à la lysogénie. Ann. Inst. Pasteur84 222–224.Google Scholar
  15. Luria, S. E. 1964. On the mechanisms of action of colicins. Ann. Inst. Pasteur107 suppl. novembre, 67–73.Google Scholar
  16. Nomura, M. 1964. Mechanism of action of colicins. Proc. Nat. Acad. Sci. U.S.52 1514–1521.Google Scholar
  17. Nomura, M. andNakamura, M. 1962. Reversibility of inhibition of nucleic acids and protein synthesis by colicin K. Biochem. Biophys. Res. Commun.7 306–309.PubMedGoogle Scholar
  18. Reeves, P. 1965. The bacteriocins. Bacteriol. Rev.29 24–45.Google Scholar

Copyright information

© Swets & Zeitlinger 1966

Authors and Affiliations

  • A. H. Stouthamer
    • 1
  • G. A. Tieze
    • 1
  1. 1.Microbiology Department, Botanical LaboratoryFree UniversityAmsterdamThe Netherlands

Personalised recommendations