Abstract
A comparative study was made of the susceptibility of 11 cell lines of human and animal origin, the WI-38 cell strain and fresh cultures of human thyroid, monkey kidney and hamster embryo tissues to certain human viruses. The animal cell lines were derived from monkey, rabbit, mouse, pig and calf tissues. The viruses used were strains of influenza A2 and B viruses, parainfluenza viruses types 1, 2 and 3, RS virus, adenoviruses types 3, 4 and 21, poliovirus type 1 and Coxsackie A type 21 and Coxsackie B type 3 viruses.
Cell lines derived from nonprimate tissues were generally less susceptible than cell cultures of human and simian origin. The combined use of fresh cultures of human thyroid and monkey kidney tissues and of a human cell line seems to provide a satisfactory indicator system for the viruses employed in this study.
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This work was supported in part by the United States Department of the Army through its European Research Office.
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Peutz-de Jong, M., Mes, A. & van der Veen, J. Susceptibility of cell lines of primate and nonprimate origin to certain human viruses. Antonie van Leeuwenhoek 32, 162–170 (1966). https://doi.org/10.1007/BF02097456
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DOI: https://doi.org/10.1007/BF02097456