Abstract
415 male out-patients were studied by serological means (complement-fixation with various viral antigens, hemagglutination-inhibition with adenoviruses of subgroup II). The conclusion was reached that the viruses investigated do not play a major role in the natural history of chronic obstructive lung disease. This is based on the following observations:
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a)
The rate of viral infections associated with respiratory disease or acute exacerbations of the bronchitis is low (see Tables 2 and 6).
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b)
Respiratory disease before the first examination is not caused by these viruses to any appreciable extent (see Table 3).
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c)
Antibody level in patients' sera against individual viruses or groups of viruses do not indicate protection against subsequent respiratory disease or against a deterioration of bronchial function (see Tables 4 and 5).
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Klaer, W., Reinert, B., Trendelenburg, F. et al. Virus infections and the natural history of chronic obstructive lung disease. Pneumonologie 142, 1–6 (1970). https://doi.org/10.1007/BF02095936
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DOI: https://doi.org/10.1007/BF02095936