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Identification of fetal blood stains by radioimmunoassay of α1-fetoprotein

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Summary

Radioimmunoassay of α1-fetoprotein(AFP) for medico-legal identification of fetal blood stains using a commercial kit is described. The AFP content in fetal blood stains on filter paper ranged from 21 – 320 ng/9 mm2. The protein was detected in stains of adult blood and retroplacental blood in only negligible amounts. Aging of the blood stains did not influence the values up to 1 month. The method is simple and sensitive enough for application to medico-legal-practice.

Zusammenfassung

Es wird die radioimmunologische Bestimmung von α1-Fetoprotein(AFP) zum forensischen Nachweis von Fetalblutspuren unter Verwertung eines kommerziellen Bestimmungsansatzes beschrieben. Der Gehalt von AFP in Fetalblutspuren auf Filterpapier betrug 21–320 ng/mm2. In Spuren von Erwachsenenblut sowie Retroplazentarblut konnte das Protein nur in äußerst geringfügigen Konzentrationen nachgewiesen werden. Das Spurenalter beeinflußte die Bestimmung bis zu 1 Monat nicht. Die Methode ist einfach und empfindlich genug für die gerichtsmedizinische Praxis.

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Authors and Affiliations

  1. Department of Legal Medicine, Nagoya University School of Medicine, Nagoya, Japan

    Yoshinao Katsumata, Masakazu Oya, Osamu Suzuki & Akira Kido

Authors
  1. Yoshinao Katsumata
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  2. Masakazu Oya
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  3. Osamu Suzuki
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  4. Akira Kido
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Katsumata, Y., Oya, M., Suzuki, O. et al. Identification of fetal blood stains by radioimmunoassay of α1-fetoprotein. Z Rechtsmed 82, 323–326 (1979). https://doi.org/10.1007/BF02092044

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  • DOI: https://doi.org/10.1007/BF02092044

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