Digestive Diseases and Sciences

, Volume 39, Issue 10, pp 2243–2243 | Cite as

Interleukin-2 and interferon-γ producing cells in the lamina propria in celiac disease

  • Emma J. Breese
  • Parveen Kumar
  • Michael J. Farthing
  • Thomas T. MacDonald
Letter To The Editor

Keywords

Public Health Celiac Disease Lamina Propria Produce Cell 

References

  1. 1.
    Halstensen TS, Brandtzaeg P: Activated T lymphocytes in the celiac lesion: Non-proliferative activation (CD25) of CD4+α/β cells in the lamina propria but proliferation (Ki-67) of α/β and γ/δ cells in the epithelium. Eur J Immunol 23:505–510, 1993PubMedGoogle Scholar
  2. 2.
    Halstensen T, Scott H, Fausa O, Brandtzaeg P: Gluten stimulation of celiac mucosain vitro induces activation (CD25) of lamina propria CD4+T cells and macrophages but no crypt-cell hyperplasia. Scand J Immunol 38:581–590, 1993PubMedGoogle Scholar
  3. 3.
    Lundin KEA, Scott H, Hansen T, Paulsen G, Halstensen TS, Fausa O, Thorsby E, Sollid LM: Gliadin-specific, HLA-DQ(α1*0501,β1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients. J Exp Med 178:187–196, 1993PubMedGoogle Scholar
  4. 4.
    Lionetti P, Spencer J, Breese EJ, Murch SH, Taylor J, MacDonald TT: Activation of mucosal Vβ3+T cells and tissue damage in human small intestine by the bacterial superantigen,Staphylococcus aureus enterotoxin B. Eur J Immunol 23:664–668, 1993PubMedGoogle Scholar
  5. 5.
    Breese E, Braegger CP, Corrigan CJ, Walker-Smith JA, MacDonald TT: Interleukin-2 and interferon γ-secreting T cells in normal and diseased human intestinal mucosa. Immunology 78:127–131, 1993PubMedGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • Emma J. Breese
    • 1
  • Parveen Kumar
    • 1
  • Michael J. Farthing
    • 1
  • Thomas T. MacDonald
    • 1
  1. 1.Department of Paediatric Gastroenterology and GastroenterologySt. Bartholomews HospitalLondonUK

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