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Digestive Diseases and Sciences

, Volume 39, Issue 10, pp 2243–2243 | Cite as

Interleukin-2 and interferon-γ producing cells in the lamina propria in celiac disease

  • Emma J. Breese
  • Parveen Kumar
  • Michael J. Farthing
  • Thomas T. MacDonald
Letter To The Editor

Keywords

Public Health Celiac Disease Lamina Propria Produce Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Halstensen TS, Brandtzaeg P: Activated T lymphocytes in the celiac lesion: Non-proliferative activation (CD25) of CD4+α/β cells in the lamina propria but proliferation (Ki-67) of α/β and γ/δ cells in the epithelium. Eur J Immunol 23:505–510, 1993PubMedGoogle Scholar
  2. 2.
    Halstensen T, Scott H, Fausa O, Brandtzaeg P: Gluten stimulation of celiac mucosain vitro induces activation (CD25) of lamina propria CD4+T cells and macrophages but no crypt-cell hyperplasia. Scand J Immunol 38:581–590, 1993PubMedGoogle Scholar
  3. 3.
    Lundin KEA, Scott H, Hansen T, Paulsen G, Halstensen TS, Fausa O, Thorsby E, Sollid LM: Gliadin-specific, HLA-DQ(α1*0501,β1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients. J Exp Med 178:187–196, 1993PubMedGoogle Scholar
  4. 4.
    Lionetti P, Spencer J, Breese EJ, Murch SH, Taylor J, MacDonald TT: Activation of mucosal Vβ3+T cells and tissue damage in human small intestine by the bacterial superantigen,Staphylococcus aureus enterotoxin B. Eur J Immunol 23:664–668, 1993PubMedGoogle Scholar
  5. 5.
    Breese E, Braegger CP, Corrigan CJ, Walker-Smith JA, MacDonald TT: Interleukin-2 and interferon γ-secreting T cells in normal and diseased human intestinal mucosa. Immunology 78:127–131, 1993PubMedGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • Emma J. Breese
    • 1
  • Parveen Kumar
    • 1
  • Michael J. Farthing
    • 1
  • Thomas T. MacDonald
    • 1
  1. 1.Department of Paediatric Gastroenterology and GastroenterologySt. Bartholomews HospitalLondonUK

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