Age and smoking dependency of the single-breath oxygen test in healthy subjects
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Normal values for the standardized single breath oxygen test of Comroe and Fowler  were obtained in 106 males (38 smokers) and 48 females (non-smokers). There was a significant positive relationship between age and nitrogen gradient in male and female non-smokers, as well as in male smokers. No difference in the slope of the nitrogen gradient with age was observed between male non-smokers and females. The slope was steeper in male smokers than in non-smokers. The nitrogen gradient was significantly higher in smokers over 35 years of age than in non-smokers.
KeywordsOxygen Public Health Nitrogen Healthy Subject Positive Relationship
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