, Volume 147, Issue 1, pp 46–51 | Cite as

Age and smoking dependency of the single-breath oxygen test in healthy subjects

  • Dan C. StĂnescu


Normal values for the standardized single breath oxygen test of Comroe and Fowler [2] were obtained in 106 males (38 smokers) and 48 females (non-smokers). There was a significant positive relationship between age and nitrogen gradient in male and female non-smokers, as well as in male smokers. No difference in the slope of the nitrogen gradient with age was observed between male non-smokers and females. The slope was steeper in male smokers than in non-smokers. The nitrogen gradient was significantly higher in smokers over 35 years of age than in non-smokers.


Oxygen Public Health Nitrogen Healthy Subject Positive Relationship 
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Copyright information

© Springer-Verlag 1972

Authors and Affiliations

  • Dan C. StĂnescu
    • 1
  1. 1.Cardiopulmonary Laboratory, Department of Occupational DiseasesHospital Colentina and Institute of Hygiene and Public HealthBucharestRomania

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