International Urology and Nephrology

, Volume 6, Issue 3–4, pp 239–242 | Cite as

The utilization of glucose in the brain slices during uraemia

  • Eva Valovičová
  • V. Spustová
  • R. Dzúrik
  • P. Černáček
Article
  • 17 Downloads

Abstract

Rat brain cortex slices were incubated in diluted sera obtained from patients with renal failure and from healthy persons. It was found that uraemic sera inhibited glucose uptake and the incorporation of14C-D-glucose into aspartate, glutamate and gamma-aminobutyrate (GABA). The concentration of these amino acids in the brain slices did not change.

Keywords

Public Health Glucose Aspartate Glutamate Renal Failure 

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Copyright information

© Akadémiai Kiadó 1974

Authors and Affiliations

  • Eva Valovičová
    • 1
  • V. Spustová
    • 1
  • R. Dzúrik
    • 1
  • P. Černáček
    • 1
  1. 1.3rd Medical Clinic, Comenius University Medical School and Research Laboratory of Experimental TherapyInstitute of Human NutritionBratislavaCzechoslovakia

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