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Correlation of lower esophageal mucosal ring and lower esophageal sphincter pressure

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Abstract

We assessed the relationship of lower esophageal sphincter pressure (LESP) to presence and absence of lower esophageal mucosal ring (LEMR) in 66 patients to determine if the LEMR was more likely related to prolonged sphincter hypotension. This potential relationship is of interest because LEMR may be due to reflux esophagitis. Each patient had radiographic and manometric studies, and both examinations were done within one week of each other. The mean LESP in patients with LEMR was 23.8 mm Hg (range 4.2–64 mm Hg) compared to 28.7 mm Hg (range 8–59 mm Hg) in patients without LEMR; the difference was not statistically significant. Patients with LEMR were also divided into three subgroups according to the diameter of the rings (≤13 mm, 14–19 mm, ≥20 mm). There was no significant relationship between the caliber of LEMR and LESP (P>0.05). Presence of LEMR did not affect the amplitude or duration of primary esophageal peristalsis. These results do not support a relationship between LEMR and prolonged LESP hypotension or abnormal esophageal motility. However, other pathogenetic mechanisms involved in producing reflux esophagitis not related to prolonged sphincter hypotension were not studied.

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References

  1. Ott DJ, Gelfand DW, Wu WC, Castell DO: Esophagogastric region and its rings. AJR 142:281–287, 1984

    Google Scholar 

  2. Ott DJ, Katz PO, Wu WC: Anti-reflux barrier.In Gastroesophageal Reflux Disease: Pathogenesis, Diagnosis, Therapy. DO Castell, WC Wu, DJ Ott (eds). Mount Kisco, New York, Futura Publishing Company, 1985, pp 35–54

    Google Scholar 

  3. Ott DJ, Wu WC, Gelfand DW: Reflux esophagitis revisited: Prospective analysis of radiologic accuracy. Gastrointest Radiol 6:1–7, 1981

    Google Scholar 

  4. Johnson LF, DeMeester TR, Haggitt RC: Endoscopic signs for gastroesophageal reflux objectively evaluated. Gastrointest Endosc 22:151–155, 1976

    Google Scholar 

  5. Cohen S, Harris LD: Does hiatus hernia affect competence of the gastroesophageal sphincter? N Engl J Med 284:1053–1056, 1971

    Google Scholar 

  6. Chen YM, Ott DJ, Gelfand DW, Munitz HA: Multiphasic examination of the esophagogastric region for strictures, rings and hiatal hernia: evaluation of the individual techniques. Gastrointest Radiol 10:311–316, 1985

    Google Scholar 

  7. Ott DJ, Richter JE, Chen YM, Wu WC, Gelfand DW, Castell DO: Esophageal radiography and manometry: Correlation in 172 patients with dysphagia. AJR 149:307–311, 1987

    Google Scholar 

  8. Richter JE, Wu WC, Johns DN, Blackwell JN, Nelson JL, Castell JA, Castell DO: Esophageal manometry in 95 healthy adult volunteers. Variability of pressures with age and frequency of “abnormal” contractions. Dig Dis Sci 32:583–592, 1987

    Google Scholar 

  9. Ahtaridis G, Snape WJ Jr, Cohen S: Lower esophageal sphincter pressure as an index of gastroesophageal acid reflux. Dig Dis Sci 26:993–998, 1981

    Google Scholar 

  10. Wolf BS, Brahams SA, Khilnani MT: The incidence of hiatus hernia in routine barium meal examination. Mt Sinai J Med NY 26:598–600, 1959

    Google Scholar 

  11. Wright RA, Hurwitz AL: Relationship of hiatal hernia to endoscopically proved reflux esophagitis. Dig Dis Sci 24:311–313, 1979

    Google Scholar 

  12. Ott DJ, Gelfand DW, Chen YM, Wu WC, Munitz HA: Predictive relationship of hiatal hernia to reflux esophagitis. Gastrointest Radiol 10:317–320, 1985

    Google Scholar 

  13. Chen YM, Gelfand DW, Ott DJ, Munitz HA: Natural progression of the lower esophageal mucosal ring. Gastrointest Radiol 12:93–98, 1987

    Google Scholar 

  14. Jamieson J, Hinder RA, DeMeester TR, Litchfield D, Barlow A, Bailey RT Jr: Analysis of thirty-two patients with Schatzki's ring. Am J Surg 158:563–566, 1989

    Google Scholar 

  15. Eckardt VF, Adami B, Hücker H, Leeder H: The esophagogastric junction in patients with asymptomatic lower esophageal mucosal rings. Gastroenterology 79:426–430, 1980

    Google Scholar 

  16. Marshall JB, Kretschmar JM, Diaz-Arias AA: Gastroesophageal reflux as a pathogenic factor in the development of symptomatic lower esophageal rings. Arch Intern Med 150:1669–1672, 1990

    Google Scholar 

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Authors and Affiliations

  1. From the Departments of Radiology and Medicine, Wake Forest University, Bowman Gray School of Medicine, 27157-1088, Winston-Salem, North Carolina

    Michael Y. M. Chen MD, David J. Ott MD, Donna L. Donati MD, Wallace C. Wu MB, BS & David W. Gelfand MD

Authors
  1. Michael Y. M. Chen MD
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  2. David J. Ott MD
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  3. Donna L. Donati MD
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  4. Wallace C. Wu MB, BS
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  5. David W. Gelfand MD
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Chen, M.Y.M., Ott, D.J., Donati, D.L. et al. Correlation of lower esophageal mucosal ring and lower esophageal sphincter pressure. Digest Dis Sci 39, 766–769 (1994). https://doi.org/10.1007/BF02087421

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  • DOI: https://doi.org/10.1007/BF02087421

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