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Prediction of radiographic severity of renal osteodystrophy by serum values

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Abstract

Renal osteodystrophy, a frequent complication of chronic renal failure, is usually assessed by periodic X-rays of bone which are both poorly reproducible and expensive. Seeking a better screening test for osteodystrophy, we evaluated the usefulness of serum alkaline phosphatase as a predictor of bone disease and of hyperparathyroidism. Alkaline phosphatase, despite nonspecificity, correlates with the severity of osteodystrophy and with the increase in serum parathyroid hormone concentration. Serial measurements of alkaline phosphatase can predict changes in these parameters.

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Authors and Affiliations

  1. Farmington and St. Francis Hospital, University of Connecticut Health Center, Hartford, Connecticut, USA

    L. E. Guerra, J. A. Amato, M. A. Galen & J. F. Maher

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  1. L. E. Guerra
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  2. J. A. Amato
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  3. M. A. Galen
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  4. J. F. Maher
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Guerra, L.E., Amato, J.A., Galen, M.A. et al. Prediction of radiographic severity of renal osteodystrophy by serum values. International Urology and Nephrology 12, 65–72 (1980). https://doi.org/10.1007/BF02085384

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  • DOI: https://doi.org/10.1007/BF02085384

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