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Cellular damage and recovery of the early developing mouse eye following low dose irradiation. I. X-rays on day 8 of gestation

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Summary

The eye region of mouse embryos, irradiated with 90 rad X-rays on day 8 of gestation, was examined 24 h later for cellular damage. Besides the overall developmental retardation, the radiation insult decreased the proliferation rate and altered the mitotic phase ratio. Due to the limited extension of necrotic zones, a reduced number of dead cells was found in the irradiated optic vesicles.

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Authors and Affiliations

  1. Strahlenbiologisches Institut der Universität Zürich, August-Forel-Strasse 7, CH-8008, Zürich, Switzerland

    I. Balla, C. Michel & Hedi Fritz-Niggli

Authors
  1. I. Balla
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  2. C. Michel
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  3. Hedi Fritz-Niggli
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Additional information

Supported by the Swiss National Foundation for Scientific Research. The technical assistance of Mrs E. Frei is gratefully acknowledged.

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Balla, I., Michel, C. & Fritz-Niggli, H. Cellular damage and recovery of the early developing mouse eye following low dose irradiation. I. X-rays on day 8 of gestation. Experientia 37, 1105–1106 (1981). https://doi.org/10.1007/BF02085038

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  • DOI: https://doi.org/10.1007/BF02085038

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