Experientia

, Volume 37, Issue 10, pp 1103–1105 | Cite as

Degradation of type I collagen fibrils synthesized by human dental pulp cells in explant culture exposed toActinomyces viscosus. Electron microscope immunotyping

  • H. Magloire
  • J. Dumont
  • J. A. Grimaud
  • A. Joffre
  • G. Benay
  • D. Herbage
Specialia
  • 10 Downloads

Summary

Actinomyces viscosus Be 66, added to pulpal cells in culture, does not cause apparent cellular damage. The extracellular matrix consists of altered collagen fibrils and thin filaments, immunochemically identified as type I collagen. They probably represent the first steps of collagen degradation.

Keywords

Collagen Electron Microscope Extracellular Matrix Fibril Collagen Fibril 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. 2.
    M. Larmas, Acta odont. scand.30, 555 (1972).Google Scholar
  2. 3.
    R. Weill, P. Lormee, M. Golberg and F. Escaig, Caries Res.11, 95 (1977).Google Scholar
  3. 4.
    C.D. Torneck, J. oral Path.6, 82 (1977).Google Scholar
  4. 5.
    H. Magloire, A. Joffre, M.L. Couble, C. Chavrier and J. Dumont, Cell. molec. Biol., in press (1981).Google Scholar
  5. 6.
    S.E. Mergenhagen and H.W. Sherp, Archs oral Biol.1, 333 (1960).Google Scholar
  6. 7.
    S. Despres, H. Metivier and R. Weill, C. r. Acad. Sci., Paris290, 41 (1980).Google Scholar
  7. 8.
    S. Edwardsson, Odont. Rev.25, suppl. 32 (1974).Google Scholar
  8. 9.
    D.L. Sumney and H.V. Jordan, J. dent. Res.53, 343 (1974).Google Scholar
  9. 10.
    H. Magloire and J. Dumont, J. Biol. buccale4, 3 (1976).Google Scholar
  10. 11.
    J.A. Grimaud, M. Druguet, S. Peyrol, O. Chevalier, D. Herbage and N. El Badrawy, J. Histochem. Cytochem.28, 1145 (1980).Google Scholar
  11. 12.
    R.C. Graham and M.J. Karnovsky, J. Histochem. Cytochem.14, 291 (1966).Google Scholar
  12. 13.
    H. Magloire, A. Joffre, J.A. Grimaud, D. Herbage, M.L. Couble, C. Chavrier and J. Dumont, Cell. molec. Biol., in press (1981).Google Scholar
  13. 14.
    I. Cournil, C.P. Leblond, J. Pomponio, A.R. Hand, L. Sederlof and G.R. Martin, J. Histochem. Cytochem.27, 1059 (1979).Google Scholar
  14. 15.
    M. Levine, R.L.P. Adams and G.C. Cowley, J. Periodont. Res.8, 296 (1973).Google Scholar
  15. 16.
    R. Duguid, F. Al Markadsi and G.C. Cowley, Archs oral Biol.25, 349 (1980).Google Scholar
  16. 17.
    K.A. Selvig, Acta odont. scand.24, 459 (1966).Google Scholar
  17. 18.
    G.C. Rose, Y. Toshihiko and C. Mahan, J. Periodont. Res.15, 53 (1980).Google Scholar
  18. 19.
    D.W. Pettigrew, J. Sodek, H.M. Wang and D.M. Brunette, Archs oral Biol.25, 269 (1980).Google Scholar

Copyright information

© Birkhäuser Verlag 1981

Authors and Affiliations

  • H. Magloire
    • 1
    • 2
    • 3
  • J. Dumont
    • 1
    • 2
    • 3
  • J. A. Grimaud
    • 1
    • 2
    • 3
  • A. Joffre
    • 1
    • 2
    • 3
  • G. Benay
    • 1
    • 2
    • 3
  • D. Herbage
    • 1
    • 2
    • 3
  1. 1.Laboratoire de Biologie Bucco-DentaireFaculté d'OdontologieLyon cedex 2(France)
  2. 2.Institut Pasteur de Lyon, ERA 819Lyon(France)
  3. 3.C.M.E.A.B.G.Faculté des SciencesVilleurbanne(France)

Personalised recommendations