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Effects of fluoride on glycosaminoglycan of cancellous and cortical bone of rabbits

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Summary

The present report deals with the effect of excessive ingestion of fluoride on glycosaminoglycan (GAG). Increase in fluoride deposition in bone, and in circulating levels of fluoride in serum, are also reported. Among the 3 constituents of GAG investigated; hexosamine, uronic acid and sulphate, the content remained unaltered except for sulphate.

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Authors and Affiliations

  1. Fluorosis Research Laboratory, Department of Anatomy, All India Institute of Medical Sciences, 110029, New Delhi, India

    A. K. Susheela & Mohan Jha

Authors
  1. A. K. Susheela
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  2. Mohan Jha
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Additional information

Acknowledgment. The authors wish to acknowledge the Department of Science and Technology (DST), Government of India, for the financial aid. One of us (M.J.) acknowledges the receipt of a Junior Research Fellowship from DST, during the tenure of which the investigations were carried out.

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Susheela, A.K., Jha, M. Effects of fluoride on glycosaminoglycan of cancellous and cortical bone of rabbits. Experientia 37, 1097–1099 (1981). https://doi.org/10.1007/BF02085034

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