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Periodic syndrome and migraine in children and adolescents

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Abstract

Many reports in the literature seem to confirm the hypothesis that the symptoms of periodic syndrome are precursors or the equivalent of migraine: the aim of this study was to assess the prevalence of periodic syndrome in a group of children and adolescents suffering from migraine in comparison with that observed in various control groups. We considered seven symptoms: recurrent vomiting and abdominal pain, migrating limb pain, vertigo, recurrent hyperthermia with no visible cause, sleep disturbances and eating disorders. The study involved 171 children divided into four groups: 42 migraineurs; 37 subjects with chronic nervous pathologies but no psychosomatic symptoms; 46 subjects with a known psychosomatic disease, and 46 healthy subjects. The prevalence of the symptoms in the different control groups was different, although the pattern was more similar in the migraineurs and psychosomatic patients than in the other control groups. The development continuum of the syndrome may support the view that periodic syndrome is predictive of the subsequent development of a psychosomatic pathology.

Sommario

Molti studi in letteratura confermano l'ipotesi che vede la sindrome periodica come un precursore o un equivalente dell'emicrania. Lo scopo di questo studio è di dimostrare la prevalenza della sindrome periodica in un gruppo di bambini e adolescenti cefalalgici confrontati con un gruppo di controllo. Sono stati considerati 7 sintomi: vomiti ricorrenti e dolori addominali, dolori migranti, febbri ricorrenti senza una causa dimostrata, vertigine, disturbi del sonno e dell'alimentazione. Sono stati studiati 171 bambini divisi in 4 gruppi: 42 emicranici, 37 soggetti con patologia cronica a carico del sistema nervoso, 46 soggetti affetti da patologia a genesi psicosomatica, 46 soggetti sani. La prevalenza dei sintomi è risultata differente rispetto al gruppo di controllo e mostra un pattern simile per gli emicranici e il gruppo di pazienti psicosomatici rispetto all'altro gruppo di controllo. La sindrome periodica può quindi essere considerata predittiva rispetto al seguente sviluppo di una patologia psicosomatica.

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Lanzi, G., Zambrino, C.A., Balottin, U. et al. Periodic syndrome and migraine in children and adolescents. Ital J Neuro Sci 18, 283–288 (1997). https://doi.org/10.1007/BF02083305

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