Pediatric Cardiology

, Volume 10, Issue 4, pp 205–211 | Cite as

Prevalence, treatment, and outcome of heart disease in live-born children: A prospective analysis of 91,823 live-born children

  • Milan Šamánek
  • Zdeněk Slavík
  • Božena Zbořilová
  • Věra Hroboňová
  • Marie Voříšková
  • Jan Škovránek


All 91,823 children born in 1980 in Bohemia (population 6.314 million; area 52,478 square kilometers) were examined at least four times during infancy and at the age of three and four years. All children who died were autopsied and those with heart disease were selected. A total of 779 children (8.223/1000 live births) were suspected by provincial pediatric cardiologists of having a heart disease. All of these were examined at the age of four years at our Center of Pediatric Cardiology. At this age heart disease was proved in 613 alive or decreased children (6.676/1000 live births), congenital cardiac malformations in 589 (6.415/1000 live births), and cardiomyopathies in 24. The most frequent congenital heart defects (CHD) were ventricular septal defect (VSD) (31.41%), atrial septal defect (ASD) (11.37%), aortic stenosis (AS) (7.64%), pulmonary stenosis (PS) (7.13%), coarctation of the aorta (CoA) (5.77%), and transposition of the great arteries (TGA) (5.43%), followed by persistent ductus arteriosus (PDA) (4.75%), atrioventricular septal defect (AVSD) and hypoplastic left heart syndrome (HLHS) (4.07% each), tetralogy of Fallot (TF) (3.56%), and pulmonary atresia (PA) (2.38%). A prevalence of less than 0.1/1000 live births was found for the remaining cardiovascular defects.

One hundred fifty-nine (25.9%) patients were admitted to our highly specialized center, 116 (19.7%) catheterized and 85 (13.9%) treated surgically, during the first four years of life. A total of 440 (71.8%) patients survived the fourth year of life. The percentage of deaths was 25.6% among those with congenital heart diseases and 71% with cardiomyopathies. The overall mortality rate was 27% in surgically and 26% in medically treated patients.

Key words

Congenital heart malformations Mortality Cardiomyopathy Congenital heart disease prevalence 


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  1. 1.
    Bierman IM, Siegel E, French FE (1965) Analysis of the outcome of all pregnancies in a community: Kanai pregnancy study.Am J Obstet Gynecol 91:37PubMedGoogle Scholar
  2. 2.
    Bound JP, Logan WFWE (1977) Incidence of congenital heart disease in Blackpool 1957–1971.Br Heart J 39:445PubMedGoogle Scholar
  3. 3.
    Carlgren LE (1959) Incidence of congenital heart disease in children born in Gothenburg 1941–1950.Br Heart J 21:40PubMedGoogle Scholar
  4. 4.
    Dickinson DF, Arnold R, Wilkinson JL (1981) Congenital heart disease among 160,480 liveborn children in Liverpool 1960–1969.Br Heart J 46:55PubMedGoogle Scholar
  5. 5.
    Ellison RC (1981) Epidemiologic contributions to the aetiology and prevention of congenital heart disease. In: Godman MJ (ed)Pediatric Cardiology, vol 4. Churchill Livingstone, Edinburgh, p 6Google Scholar
  6. 6.
    Feldt KH, Avasthey P, Yoshimasu F, Kurland LT, Titus JL (1971) Incidence of congenital heart disease in children born to residents of Olmstead Country, Minnesota 1950–1969.Mayo Clin Proc 46:794PubMedGoogle Scholar
  7. 21.
    Neel JV (1958) Study of major congenital defects in Japanese infants.Am J Hum Genet 10:398PubMedGoogle Scholar
  8. 22.
    Pleydel MJ (1960) Anencephaly and other congenital abnormalities: epidemiological study in Northamptonshire.Br Med J 1:309Google Scholar
  9. 23.
    Renwick DHG, Miller JR, Peterson D (1964) Estimates of incidence and prevalence of mongolism and of congenital heart disease in British Columbia.Can Med Assoc J 9:365Google Scholar
  10. 24.
    Richards MR, Merrits KK, Samuel MH (1955) Congenital malformations of the cardiovascular system in a series of 6503 infants.Pediatrics 15:12PubMedGoogle Scholar
  11. 25.
    Rose V, Boyd ARJ, Ashton TE (1964) Incidence of heart disease in children in the city of Toronto.Can Med Assoc J 91:95PubMedGoogle Scholar
  12. 26.
    Šamánek M (1981) Care of children with cardiovascular disease in Czechoslovakia.Cor Vasa 23:1PubMedGoogle Scholar
  13. 27.
    Šamánek M (1986) Results of first years of centralized care for children suffering from heart disease. In: Doyle EF, Engle MA, Gersony WM, Rashkin WJ, Talner NS (eds)Pediatric Cardiology. Springer-Verlag, New York, p 1153Google Scholar
  14. 28.
    Šamánek M (1989) Survival of children born with congenital heart disease.Pediatr Cardio (in press)Google Scholar
  15. 29.
    Šamánek M, Goetzová J, Benešová D (1986) Causes of death in neonates born with a heart malformation.Int J Cardiol 11:63PubMedGoogle Scholar
  16. 30.
    Wallooppillai NJ, Jayasinghe M de S (1970) Congenital heart disease in Ceylon.Br Heart J 32:304PubMedGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1989

Authors and Affiliations

  • Milan Šamánek
    • 1
  • Zdeněk Slavík
    • 1
  • Božena Zbořilová
    • 1
  • Věra Hroboňová
    • 1
  • Marie Voříšková
    • 1
  • Jan Škovránek
    • 1
  1. 1.Center of Pediatric Cardiology and Cardiovascular SurgeryUniversity Hospital MotolPragueCzechoslovakia

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