Abstract
Different parameters of coagulation were studied in 71 patients with glomerulonephritis. In comparison with normal subjects they had lower platelet counts, lower adhesion index and decreased aggregation, decreased partial thromboplastin time (46.4 per cent of patients), increased reptilase time (47.8 per cent) and other disorders. Plasma fibrin monomer soluble complexes were positive in 52.1 per cent and fibrin degradation products occurred in 14 per cent. According to the authors, in glomerulonephritis there are: a) subacute or chronic forms of disseminated intravascular coagulation; b) thrombopathy.
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Aleksiev, G. I., Bobrov, L. L.: Coagulation, fibrinolysis and kinins in glomerulonephritis.Clin. Med., 57, 72 (1979).
Barkagan, Z. S.: Haemorrhagic diseases and syndromes.Medicina, Moscow 1980.
Bick, R. Z.: Disseminated intravascular coagulation and related syndrome: Etiology, pathophysiology, diagnosis and management.Am. J. Haematol., 5, 265 (1978).
Bick, R. Z.: Disseminated intravascular coagulation: A clinical laboratory study of 48 patients.Ann. N. Y. Acad. Sci., 370, 843 (1981).
Clarkson, A. R., Seymor, A. E. Jackson, B.: Coagulation and renal disease.Med. J. Aust., 573 (1976).
Colman, R. W., Robboy, S. J., Minna, J. P.: Disseminated intravascular coagulation: A reappraisal.Ann. Rev. Med., 30, 359 (1979).
Feinstein, D.: Diagnosis and management of disseminated intravascular coagulation. The role of heparin therapy.Blood, 60, 284 (1982).
Genova, V.: Changes in coagulation in patients with acute leucosis. Thesis, Sofia, 1968.
Hamilton, P. J., Stalker, A. L., Douglas, A. S.: Disseminated intravascular coagulation: A review.J. Clin. Pathol., 31, 609 (1978).
Innerfield, J., Stone, M.: Antithrombin and heparin patterns in prethrombosis and thrombosis.Am. J. Clin. Pathol.,65, 384 (1976).
Kincaid-Smith, P.: Coagulation and renal disease.Kidney Int., 2, 183 (1972).
Kincaid-Smith, P.: Participation of intravascular coagulation in the pathogenesis of glomerular and vascular lesions.Kidney Int., 7, 242 (1975).
McKay, D. G., Phillips, L. L., Kaplan, H., Henson, J. B.: Chronic intravascular coagulation in Aleutian disease in munk.Am. J. Pathol., 50, 899 (1967).
McKay, D. G.: Clinical significance of intravascular coagulation. In: Abe T., Yamanaka, M. (eds): Disseminated Intravascular Coagulation. University of Tokyo Press 1983.
Spero, J. A., Lewis, J. A., Hasile, U.: Disseminated intravasculation.Thromb. Haemostasis, 38, 33 (1981).
Stratta, P., Canavese, C.: Coagulation and fibrinolytic studies in systemic lupus erythematosus. Haematological, urinary and tissue parameters.Thromb. Haemostas., 39, 575 (1981).
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Belovezhdov, N., Robeva, R. & Genova, V. Blood coagulation in glomerulonephritis. International Urology and Nephrology 18, 193–203 (1986). https://doi.org/10.1007/BF02082608
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DOI: https://doi.org/10.1007/BF02082608