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Prophylactic use of topical adriamycin after transurethral resection of transitional cell bladder tumours

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Abstract

Thirty-five patients with carcinoma of the bladder were subjected to weekly intravesical instillation treatment with 30 mg adriamycin/50 ml solution for a period of 6 weeks following transurethral resection of the tumour. The oncolytic and thus recurrence-preventive value of treatment was determined by endoscopic controls with exploratory excisions and exfoliative cytology. All in all, a recurrence-free rate was found in 77% over a minimum observation period of one year. These results are definitely better than those of comparable instillation treatments with surface-active or immunologically active substances.

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Flamm, J., Grof, F. Prophylactic use of topical adriamycin after transurethral resection of transitional cell bladder tumours. International Urology and Nephrology 17, 143–147 (1985). https://doi.org/10.1007/BF02082485

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