Abstract
In the anaesthetized dog total renal blood flow (RBF) and its intrarenal distribution were investigated by the radioactive microsphere technique under control conditions and after various experimental interventions.
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(i)
In five control series performed within the last four years, there was a small but significant scatter in total RBF, due entirely to changes in inner cortical (IC) perfusion, while outer cortical (OC) perfusion proved to be constant.
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(ii)
Repeated measurements in the same dog, performed after 1 h interval, revealed constancy of total RBF with some inward shifting in cortical perfusion.
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(iii)
Surgical intervention or manipulation of the kidney did not alter total RBF but led to an increase in IC, compensated by a decrease in OC perfusion.
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(iv)
The possible role of local intrarenal hormones (angiotensin and prostaglandin) in the above changes is discussed.
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László, K., Szőcs, É., Juszkó, J. et al. Reliability of the measurement of intrarenal haemodynamics in the dog, as determined by the radioactive microsphere technique. International Urology and Nephrology 13, 207–220 (1981). https://doi.org/10.1007/BF02082418
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DOI: https://doi.org/10.1007/BF02082418