International Urology and Nephrology

, Volume 8, Issue 2, pp 161–169 | Cite as

Peritoneal clearances in scleroderma and diabetes mellitus: Effects of intraperitoneal isoproterenol

  • K. D. Nolph
  • L. Miller
  • B. S.
  • F. C. Husted
  • P. Hirszel
Article

Abstract

Reduced peritoneal clearances of creatinine and urate were demonstrated repeatedly in a patient with scleroderma and a patient with diabetes mellitus. Urea clearances were not significantly different from usual values. The findings suggest decreased peritoneal membrane permeability and/or area (if urea clearance is flow limited). Clearances increased to usual values with intraperitoneal isoproterenol in the patient with diabetes. There was no effect of isoproterenol in the patient with scleroderma.

Keywords

Public Health Permeability Diabetes Mellitus Urea Creatinine 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Brown, S. T., Ahearn, D. J., Nolph, K. D.: Reduced peritoneal clearances in scleroderma increased by intraperitoneal isoproterenol.Ann. Int. Med. 78, 891 (1973).PubMedGoogle Scholar
  2. 2.
    Henderson, L. W., Nolph, K. D.: Altered permeability of the peritoneal membrane after using hypertonic peritoneal dialysis fluid.J. Clin. Invest. 48, 992 (1969).PubMedGoogle Scholar
  3. 3.
    Henry, R. J., Chiamori, N.: On the direct Nesslerization of ammonia formed by urease treatment of blood serum, and urine.Am. J. Clin. Pathol. 29, 277 (1958).PubMedGoogle Scholar
  4. 4.
    Henry, R. J., Sobel, C., Kim, J.: A modified carbonate-phosphotungstate method for the the determination of uric acid and comparison with the spectrophotometric uricase method.Am. J. Clin. Pathol. 28, 152 (1957).PubMedGoogle Scholar
  5. 5.
    Karnovsky, M. J.: The ultrastructural basis of capillary permeability studied with peroxidase as a tracer.J. Cell Biol. 35, 213 (1967).PubMedGoogle Scholar
  6. 6.
    Nolph, K. D., Stolz, M. L., Maher, J. F.: Altered peritoneal permeability in patients with systemic vasculitis.Ann. Int. Med. 75, 753 (1971).PubMedGoogle Scholar
  7. 7.
    Nolph, K. D., Whitcomb, M. E., Schrier, R. W.: Mechanisms for inefficient peritoneal dialysis in acute renal failure associated with heat stress and exercise.Ann. Int. Med. 71, 317 (1969).PubMedGoogle Scholar
  8. 8.
    Owen, J. A., Iggo, B., Scandrett, F. J., Stewart, C. P.: The determination of creatinine in plasma or serum, and in urine; a critical examination.Biochem. J. 58, 426 (1954).PubMedGoogle Scholar
  9. 9.
    Romeo, S. G., Whalen, R. E., Tindall, J. P.: Intra-arterial administration of reserpine.Arch. Int. Med. 125, 825 (1970).Google Scholar
  10. 10.
    Willerson, J. T., Thompson, R. H., Hookman, P., Herdt, J., Decker, J. L.: Reserpine in Raynaud's disease and phenomenon. Short-term response to intra-arterial injection.Ann. Int. Med. 72, 17 (1970).PubMedGoogle Scholar
  11. 11.
    Winkelmann, R. K., Kierland, R. R., Perry, H. O., Muller, S. A., Sams, W. M. Jr.: Management of scleroderma.Mayo Clin. Proc. 46, 128 (1971).PubMedGoogle Scholar

Copyright information

© Akadämiai Kiadó 1976

Authors and Affiliations

  • K. D. Nolph
    • 1
  • L. Miller
    • 1
  • B. S.
    • 1
  • F. C. Husted
    • 1
  • P. Hirszel
    • 1
  1. 1.Division of Nephrology, Department of MedicineUniversity of Missouri Medical Center, Veterans Administration HospitalColumbiaU.S.A.

Personalised recommendations