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Vascular changes in the urinary bladder wall after irradiation

An experimental study in rabbits with angiography and scanning electron microscopy of vascular casts

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Abstract

Seven adult rabbits were used to study radiation-induced vascular changes in the urinary bladder by angiography and scanning electron microscopy of vascular casts.

The angiographic studies, in which a magnification techniques was used, revealed a state of hypervascularization in the irradiated area of the bladder. With the angiographic method, however, it was not possible to visualize specific radiation-induced vascular changes within the irradiated area of the urinary bladder. Scanning electron microscopy of vascular casts made possible a detailed study of finer vessels in which typical radiation changes, teleangiectases, could be demonstrated.

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References

  1. Adams, D. F., Olin, T. B., Redman, H. C.: Catheterization of arteries in the rabbit.Radiology 84, 531 (1965).

    PubMed  Google Scholar 

  2. Brownson, R. H., Suter, D. B., Oliver, J. L. et al.: Histochemical and histological changes induced in rat brain by X-irradiation. In: Response of the Nervous System to Ionizing Radiation, p. 307. Edited by T. J. Haley and R. S. Snider. Little, Brown & Co, Boston 1964.

    Google Scholar 

  3. Carlson, H. C., Williams, M., Childs, D. S., Dockerty, M. B., Janes, J. M.: Microangiography of bone in study of radiation changes.Radiology 74, 113 (1960).

    PubMed  Google Scholar 

  4. Ekulund, L., Olin, T.: Catheterization of arteries in rats.Invest. Radiol. 5, 69 (1970).

    PubMed  Google Scholar 

  5. Göthlin, J., Carter, A. M.: Pelvic angiography in the female rabbit.Invest. Radiol. 4, 45 (1969).

    PubMed  Google Scholar 

  6. Gassler, O.: Microangiographic studies of changes in the cerebral vessels after irradiationActa Radiol. 4, 395 (1956).

    Google Scholar 

  7. Hassler, O., Hietala, S. O.: Angiographic abnormalities in the urinary bladder wall after irradiation. Part I. Animal experiments. Part II. Clinical investigation.Acta Radiol. Suppl. 328 (1973).

  8. Hassler, O., Movin, A.: Microangiographic studies on changes in the cerebral vessels after irradiation. 1. Lesions in the rabbit produced by 60-Co gamma-rays, 195 kV and 34 MV roentgen rays.Acta Radiol. 4, 281 1966).

    Google Scholar 

  9. Hietala, S. O., Winblad, B., Hassler, O.: Angiographic and morphological changes in the urinary bladder wall after irradiation.Int. Urol. Nephrol. (in press).

  10. Lindell, S. B., Olin, T.: Catheterization of the renal arteries in dogs and cats.Acta phys. Scand. 39, 73 (1957).

    Google Scholar 

  11. Ljungqvist, A., Unge, G., Lagergren, C., Notter, G.: The intrarenal vascular alterations in radiation nephritis and their relationship to the development of hypertension.Acta path. microbiol. Scand. 79, 629 (1971).

    Google Scholar 

  12. Murakami, T.: Application of the scanning electron microscope to the study of the fine distribution of the blood vessels.Arch. histol. Jap. 32, 445 (1970).

    Google Scholar 

  13. Murakami, T., Miyoshi, M., Fujita, T.: Glomerular vessels of the rat kidney with special reference to double efferent arterioles. A scanning electron microscope study of corrosion casts.Arch. histol. Jap. 23, 179 (1971).

    Google Scholar 

  14. Rubin, P., Casarett, G. W., Grise, J.: The vascular pathophysiology of an irradiated graft.Amer. J. Roentgenol. 83, 1097 (1960).

    PubMed  Google Scholar 

  15. Rubin, P., Casarett, G. W., Kurohara, S. S., Fujita, M.: Microangiography as a technique. Radiation effects versus artifact.Amer. J. Roentgenol. 92, 378 (1964).

    PubMed  Google Scholar 

  16. Rubin, P., Casarett, G. W.: Clinical Radiation Pathology. W. B. Saunders Company, Philadelphia-London-Toronto 1968.

    Google Scholar 

  17. Scanlon, G. T.: Vascular alteration in the irradiated rabbit kidney. A microangiographic study.Radiology 94, 401 (1970).

    PubMed  Google Scholar 

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Hietala, S.O., Winblad, B. Vascular changes in the urinary bladder wall after irradiation. International Urology and Nephrology 8, 121–128 (1976). https://doi.org/10.1007/BF02082207

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