International Urology and Nephrology

, Volume 13, Issue 1, pp 95–104 | Cite as

The use of pediatric cadaver kidneys in renal transplantation (Experience with 97 cases and comparison with adult kidneys)

  • L. G. Managadze
  • H. Oesterwitz
  • D. Scholz
  • G. May
  • M. Mebel
Article

Abstract

Pediatric cadaver donors are an important pool of kidneys for human allotransplantation. Experiences with 97 transplantations of pediatric cadaveric kidneys (age: 4 months to 15 years) and comparison with 230 transplantations of adult kidneys (age: 16–25 and 40–68 years) are presented. The cumulative patient survival was similar in both groups, however, the graft survival was significantly lower in the pediatric donor group (p<0.05). This difference was established almost exclusively within the first 3 months after transplantation. In this group the percentage of technical complications in the first month was higher (13.4%) than in the adult kidney group (6.5%). The analysis of the whole pool of harvested kidneys shows a significantly higher rate of transplanted kidneys in the pediatric group (61%) as compared with the adult group (44.7%). In both groups the mode of arterial vascular anastomosis (end-to-end or end-to-side) does not influence the graft survival.

Further investigations on pediatric donor kidneys are necessary. The utilization of pediatric cadaveric kidneys for transplantation should be increased because 20–25% of all potential kidney donors are younger than 15 years.

Keywords

Public Health Patient Survival Renal Transplantation Graft Survival Donor Group 

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Copyright information

© Akadémiai Kiadó 1981

Authors and Affiliations

  • L. G. Managadze
    • 1
  • H. Oesterwitz
    • 1
  • D. Scholz
    • 1
  • G. May
    • 1
  • M. Mebel
    • 1
  1. 1.Kidney Transplantation Center, Berlin-Friedrichshain, Department of Urology, Division of Experimental Organ TransplantationHumboldt-University (Charité)BerlinGDR

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