Skip to main content

Circatrigintan (30±5 d) variations of the cellular component of female urethral expulsion fluid

A biometrical study


Data on the amount of uroepithelial squamous cells released into the fluid of urethral expulsions were obtained in a 37-year-old multipara by daily five consecutive repeated applications of the digital stimulation technique, carried out over the period of one and a half of her menstrual cycle. During the secretory phase of the cycle the rate of the cellular component was far higher than during the proliferative phase. These quantitative biometrically analysed data provide a complementary picture to the qualitative cytological changes of uroepithelial squamous cells occurring during the menstrual cycle that have been reported so far.

This is a preview of subscription content, access via your institution.


  1. Bernhard, G., Thierry, B., Haour, P.: Aspects de la cytologie urétrale au cours de la grossesse et du post-partum.Sem. Hôp. (Paris),55, 769 (1979).

    Google Scholar 

  2. Bohlen, J. G.: “Female ejaculation” and urinary stress incontinence.J. Sexol. Res., 18, 360 (1982).

    Google Scholar 

  3. Del Castillo, E. B., Argonz, J., Mainini, C. G.: Cytological cycle of the urinary sediment and its parallelism with the vaginal cycle.J. Clin. Endocrinol. Metab., 8, 76 (1948).

    Google Scholar 

  4. Egloff, B.: Pathologische Anatomie der weiblichen Urethra. In: Lubarsch, O. (ed.): Handbuch der Pathologischen Anatomie, VII/4: Weibliche Geschlechtsorgane. Springer Verlag, Berlin-Heidelberg-New York 1972.

    Google Scholar 

  5. Grafenberg, E.: The role of urethra in female orgasm.Int. J. Sexol., 3, 145 (1950).

    Google Scholar 

  6. Hedberg, G.: Squamous epithelium of the vaginal type in the female urethra.Gynaecologia, 128, 254 (1949).

    Google Scholar 

  7. Hermosa, A. R.: Urccytogram. In: Ayala, M. J., Ortiz, F. N. (eds): Gynecological Cytopathology. Mosby, Saint Louis 1978.

    Google Scholar 

  8. Koss, L. G.: Cytologic evaluation of the endocrine status of the woman. In: Koss, K. G. (ed.): Diagnostic Cytology and its Histopathologic Bases. Lippincott, Philadelphia-Toronto 1979.

    Google Scholar 

  9. Langreder, W.: Die weibliche Urethra, funktionelle Anatomie, Pathologie und Therapie des Verschlussmechanismus.Zentralbl. Gynaekol., 78, 561 (1956).

    Google Scholar 

  10. Langreder, W.: Gynäkologische Urologie. Georg Thieme, Stuttgart 1961.

    Google Scholar 

  11. Lencioni, L. J., Staffieri, J. J.: Urocytogram diagnosis of sexual precocity.Acta Cytol. (Baltimore),13, 382 (1969).

    Google Scholar 

  12. O'Morchoe, P. J., O'Morchoe, C. C. C.: Method for urinary cytology in endocrine assessment.Acta Cytol. (Baltimore),11, 145 (1967).

    Google Scholar 

  13. Rohlf, F. J., Sokal, R. R.: Statistical Tables. W. H. Freeman, San Francisco 1981.

    Google Scholar 

  14. Sokal, R. R., Rohlf, F. J.: The Principles and Practice of Statistics in Biological Research. W. H. Freeman, San Francisco 1981.

    Google Scholar 

  15. Von Rütte, B., Delnon, I.: Die Urethralzytologie und ihre Bedeutung zur Diagnose hormonal bedingter Miktionsstörungen.Praxis, 57, 555 (1968).

    PubMed  Google Scholar 

  16. Wesson, L.: Diurnal circadian rhythms of renal function and electrolyte excretion in heart failure.Int. J. Chronobiol., 6, 109 (1979).

    PubMed  Google Scholar 

  17. Zaviačič M., Zaviačičová, A., Holomáň, I. K.: Weibliche Ejakulation. Die Zusammensetzung des urethralen Ejakulats der Frau das mit der Grafenberg-Technik gewonnen wurde.Sexualmedizin (submitted for publication).

  18. Zaviačič, M., Holomáň, I. K., Molčan, J., Zaviačičová, A.: Weibliche Ejakulation. Einleitung in die Technik der Stimulation des Grafenberg-Spots der Vagina.Sexualmedizin (submitted for publication).

  19. Zaviačič, M., Holomáň, I. K., Zaviačičová, A., Molčan, J.: Female urethral expulsions evoked by local digital stimulation of the vagina. Sexological aspects and morphological analysis of the “urethral” fluid and its importance for clinical medicine.Arch. Sex. Behav. (submitted for publication).

  20. Zaviačič, M., Brozman, M., Holomáň, I. K., Zaviačičová, A., Oberučová, J.: New information on the paraurethral (Skene's) ducts and glands in the female.Bratisl. Lek. Listy, 79, 533 (1983).

    PubMed  Google Scholar 

  21. Zaviačič, M., Zajičková, M., Zaviačičová, A., Oberučová, J.: The human female urethra. Histology and histochemical findings.Acta Histochem. (Jena) (in press).

  22. Zaviačič, M., Jakubovský, J., Polák, Š., Zaviačičová, A., Holomáň, I. K.: Rhythmic changes of human female uroepithelial squamous cells during menstrual cycle. Transmission and scanning electron microscopic study.Int. Urol. Nephrol., 16, 301 (1984).

    PubMed  Google Scholar 

  23. Zaviačič, M., Šuska, P., Holomáň, I. K., Zaviačičová, A., Zajíčková, M., Blažeková, J.: Results of cytological methods applied on the vaginal, urethral, urine sediment and female “ejaculate” smears.Critical Study (in preparation).

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Cite this article

Zaviačič, M., Zaviačičová, A., Komorník, J. et al. Circatrigintan (30±5 d) variations of the cellular component of female urethral expulsion fluid. International Urology and Nephrology 16, 311–318 (1984).

Download citation

  • Received:

  • Issue Date:

  • DOI:


  • Public Health
  • Squamous Cell
  • Menstrual Cycle
  • Cellular Component
  • Secretory Phase