Critical appraisal of human bladder regeneration
- 19 Downloads
Two cases of complete failure of bladder wall regeneration are described. In the first case subtotal cystectomy was performed and peritoneal flap was used to repair the bladder wall. In the second, excision of the entire bladder mucosa was carried out and the was closed. Bladder tumors were indications for using the principle of hypothetical bladder regeneration in both cases. Lack of the regeneration of muscular fibers as well as of epithelium has been proved by histological examination six months after operation. The regenerative power of bladder muscle and epithelium —if any — is limited in extent. This should be borne in mind when the principle of bladder regeneration is considered in clinical practice.
KeywordsPublic Health Clinical Practice Histological Examination Critical Appraisal Wall Regeneration
Unable to display preview. Download preview PDF.
- 1.Baker, R., Kelly, T., Tehan, T., Putnam, Ch., Beaugard, E.: Subtotal cystectomy and total bladder regeneration in treatment of bladder cancer.J. Am. med. Ass. 168, 1178 (1958).Google Scholar
- 2.Baker, R., Tehan, T., Kelly, T.: Regeneration of urinary bladder after subtotal resection for carcinoma.Ann. Surg., 25, 348 (1959).Google Scholar
- 3.Baker, R., Maxted, W. C., Dipasquale, N.: Regeneration of transitional epithelium of the human bladder after total surgical excision for recurrent multiple bladder cancer: apparent tumor inhibition.J. Urol. (Baltimore)93, 593 (1965).Google Scholar
- 4.Goldstein, M. B., Dearden, L. C., Gualtieri, V.: Regeneration of subtotally cystectomized bladder patched with omentum.J. Urol. (Baltimore)97, 664 (1967).Google Scholar
- 6.Kelly, T. L., Baker, R.: Regeneration of the bladder in infancy.J. Urol. (Baltimore)96, 899 (1967).Google Scholar
- 7.Liang, D. S.: Mechanical force as a factor in regeneration of the bladder.J. Urol. (Baltimore)96, 304 (1966).Google Scholar
- 8.McDonald, J. H., Deniz, E.: Ivalon cystoplasty.J. Urol. (Baltimore)88, 511 (1962).Google Scholar
- 13.Hradec, E.: Operations for enlargement and substitution of the urinary bladder preserving the voiding through urethra.Urol. int. 22, 84 (1967).Google Scholar