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Immunoglobulins as targeting agents for liposome encapsulated drugs

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Abstract

Recent literature dealing with the immunoglobulin-liposome combination as a tool for drug targeting is reviewed. Mechanisms for binding of immunoglobulins to liposomes are discussed. Results obtained so far by using this concept both to induce specific liposome-cell interactions inin vitro cell cultures and to target drug containing liposomes to selected tissues in animal studies are evaluated.

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Authors and Affiliations

  1. Department of Pharmaceutics, Pharmaceutical Laboratory, University of Utrecht, Catharijnesingel 60, 3511, GH Utrecht, The Netherlands

    P. A. H. M. Toonen & D. J. A. Crommelin

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  1. P. A. H. M. Toonen
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  2. D. J. A. Crommelin
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Toonen, P.A.H.M., Crommelin, D.J.A. Immunoglobulins as targeting agents for liposome encapsulated drugs. Pharmaceutisch Weekblad Scientific Edition 5, 269–280 (1983). https://doi.org/10.1007/BF02074854

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