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Agents and Actions

, Volume 20, Issue 3–4, pp 174–177 | Cite as

Bacteria and their products peptidoglycan and teichoic acid potentiate antigen-induced histamine release in allergic patients

  • S. Norn
  • J. O. Jarløv
  • C. B. Jensen
  • P. Clementsen
  • B. T. Dahl
  • F. Espersen
  • P. Stahl Skov
Histamine Release

Abstract

Histamine release was examined in leukocyte suspensions from patients allergic to grass pollen, mite or cat dander or to bacteria (antigen). When the cells were challenged with specific antigen plus bacteria to which the person was not sensitized, these bacteria were found to potentiate the allergic histamine release. The potentiating effect by bacteria might be due to the bacterial cell wall components, peptidoglycan and teichoic acid, which mimic the effect of bacteria.

Keywords

Cell Wall Histamine Bacterial Cell Peptidoglycan Specific Antigen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Birkhäuser Verlag 1987

Authors and Affiliations

  • S. Norn
    • 1
  • J. O. Jarløv
    • 3
  • C. B. Jensen
    • 1
  • P. Clementsen
    • 1
  • B. T. Dahl
    • 1
  • F. Espersen
    • 2
  • P. Stahl Skov
    • 1
  1. 1.Department of PharmacologyUniversity of CopenhagenCopenhagenDenmark
  2. 2.Department of Clinical Microbiology atRigshospitaletDenmark
  3. 3.Hvidovre HospitalDenmark

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