Heart and Vessels

, Volume 1, Supplement 1, pp 199–203 | Cite as

Long follow-up study in patients with prior myocarditis by radionuclide methods

  • Michiaki Hiroe
  • Morie Sekiguchi
  • Machiko Take
  • Kiyoko Kusakabe
  • Akiko Shigeta
  • Koshichiro Hirosawa
Treatment And Prognosis


Ten patients with previous myocarditis were evaluated to determine cardiac conditions by Tl-201 myocardial perfusion imaging and stress radionuclide ventriculography during the follow-up of 18–102 (average 56) months; the results were compared with those from ten sex-and age-matched controls. Exercise capacity by supine bicycle ergometer was reduced in patients with myocarditis. Their resting left ventricular ejection fraction (LVEF) was 57.5%±3.9%, similar to that of controls. LVEF response to stress in myocarditis was abnormal with an increment of end-systolic volume, while in the controls LVEF increased significantly during stress. Seven of the eight patients with an abnormal ejection fraction response had constant Tl-201 perfusion defects.

This study indicates that latent left ventricular dysfunction is present in patients with prior myocarditis and that nuclear study is useful for long-term follow-up.


Leave Ventricular Ejection Fraction Myocardial Perfusion Imaging Myocarditis Perfusion Defect Leave Ventricular Ejection Fraction 
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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • Michiaki Hiroe
    • 1
  • Morie Sekiguchi
    • 2
  • Machiko Take
    • 2
  • Kiyoko Kusakabe
    • 1
  • Akiko Shigeta
    • 1
  • Koshichiro Hirosawa
    • 2
  1. 1.Department of RadiologyTokyo Women's Medical CollegeTokyoJapan
  2. 2.The Heart Institute of JapanTokyo Women's Medical CollegeTokyoJapan

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