Long follow-up study in patients with prior myocarditis by radionuclide methods
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Ten patients with previous myocarditis were evaluated to determine cardiac conditions by Tl-201 myocardial perfusion imaging and stress radionuclide ventriculography during the follow-up of 18–102 (average 56) months; the results were compared with those from ten sex-and age-matched controls. Exercise capacity by supine bicycle ergometer was reduced in patients with myocarditis. Their resting left ventricular ejection fraction (LVEF) was 57.5%±3.9%, similar to that of controls. LVEF response to stress in myocarditis was abnormal with an increment of end-systolic volume, while in the controls LVEF increased significantly during stress. Seven of the eight patients with an abnormal ejection fraction response had constant Tl-201 perfusion defects.
This study indicates that latent left ventricular dysfunction is present in patients with prior myocarditis and that nuclear study is useful for long-term follow-up.
KeywordsLeave Ventricular Ejection Fraction Myocardial Perfusion Imaging Myocarditis Perfusion Defect Leave Ventricular Ejection Fraction
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