European Journal of Pediatrics

, Volume 150, Issue 8, pp 579–581 | Cite as

Cytogenetic characterization of congenital or infantile fibrosarcoma

  • P. Dal Cin
  • P. Brock
  • M. Casteels-Van Daele
  • I. De Wever
  • B. Van Damme
  • H. Van den Berghe
Medical Genetics


Chromosome analysis of a congenital or infantile fibrosarcoma from the lower left leg of a 3-week-old baby girl showed only numerical changes involving chromosomes 11, 17 and 20. As three more cases with similar combinations of trisomies of the same chromosomes have been described, this report confirms that adult and congenital fibrosarcoma are cytogenetically different and trisomy 11 may be the key-event.

Key words

Congenital or infantile fibrosarcoma Numerical chromosome changes Chromosome 11 


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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • P. Dal Cin
    • 1
  • P. Brock
    • 2
  • M. Casteels-Van Daele
    • 2
  • I. De Wever
    • 3
  • B. Van Damme
    • 4
  • H. Van den Berghe
    • 1
  1. 1.Centre for Human GeneticsUniversity of LeuvenBelgium
  2. 2.Department of PaediatricsUniversity of LeuvenBelgium
  3. 3.Department of Oncological SurgeryUniversity of LeuvenBelgium
  4. 4.Department of PathologyUniversity of LeuvenBelgium

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