World Journal of Surgery

, Volume 16, Issue 2, pp 294–299 | Cite as

What has the surgeon to know about pathophysiology of reflux disease?

  • Bulent Sivri
  • Richard W. McCallum
World Progress In Surgery
  • 17 Downloads

Abstract

Much has been learned about the pathophysiology of gastro-esophageal reflux (GER) since it was initially described by Asher Winkelstein in 1935. With the development and refinement of esophageal function tests in the past decades, the diagnostic modalities have become available for a deliberate and systematic evaluation of antireflux mechanisms. Some of the newer concepts of the pathogenesis of reflux esophagitis are reviewed in this article.

Keywords

Systematic Evaluation Esophagitis Reflux Disease Reflux Esophagitis Diagnostic Modality 

Résumé

La connaissance sur le reflux gastro-oesophagien (RGO) a beaucoup progressé depuis sa description initiale par Asher Winkelstein en 1935. Avec le développement et le raffinement depuis 10 ans des explorations fonctionnelles oesophagiennes, nous disposons de modalités diagnostiques pour évaluer les mécanismes anti-reflux de façon systématique et judicieuse. Quelques unes des nouvelles données sur la pathogénie de l'oesophagite par reflux sont revues dans cet article.

Resumen

Mucho se ha aprendido sobre la fisiopatología del reflujo gastroesofágico (RGE) desde su descripción inicial por Asher Winkelstein en 1935. Con el desarrollo y el refinamiento de las pruebas de función esofágica en las pasadas décadas han aparecido modalidades de diagnóstico que permiten realizar una evaluación sistemática y deliberada de los mecanismos antirreflujo. En el presente artículo se revisan algunos de los nuevos conceptos sobre la patogénesis de la esofagitis por reflujo.

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Copyright information

© the Société Internationale de Chirurgie 1992

Authors and Affiliations

  • Bulent Sivri
    • 1
  • Richard W. McCallum
    • 1
  1. 1.Health Sciences Center, Division of GastroenterologyUniversity of VirginiaCharlottesvilleUSA

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