Abstract
Worldwide, the incidence and mortality rates for melanoma are increasing at an alarming rate. Recently, the recognition of dysplastic nevi as markers and potential precursors for melanoma has identified one group of individuals with an increased risk to develop this disease. Close surveillance of these individuals should improve the ability of clinicians to detect melanoma at an early stage when surgical excision of the primary tumor is curative in the majority of patients.
Résumé
Dans le monde entier, l'incidence du mélanome et la mortalité qui en découle augmentent de manière alarmante. Récemment, l'identification de certains naevi comme marqueurs et précurseurs potentiels de mélanome, a permis l'individualisation d'un groupe de sujet à haut risque pour développer un mélanome. Une surveillance étroite de cette population, à un stade où l'excision chirurgicale de la tumeur primitive peut être curative, devrait permettre d'augmenter le nombre de cas détectés par les cliniciens à un stade utile.
Resumen
En todo el mundo se informa un incremento alarmante en las tasas de incidencia y de mortalidad por melanoma. Recientemente se ha demostrado que los nevus displásicos son marcadores y precursores potenciales de melanoma, lo cual permite identificar un grupo poblacional con mayor riesgo de desarrollar esta enfermedad. El seguimiento cuidadoso de las personas que conforman este grupo debe mejorar la capacidad de la detección clínica del melanoma en una etapa temprana de su evolución, cuando la resección quirúrgica del neoplasma primario resulta curativa en la mayoría de lo pacientes.
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Rivers, J.K. The detection and management of dysplastic nevi and early melanoma. World J. Surg. 16, 166–172 (1992). https://doi.org/10.1007/BF02071516
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DOI: https://doi.org/10.1007/BF02071516