Abstract
CuCl2 is a non-competitive inhibitor whereas CuTyr2 and CuLys2 complexes are characterized by mixed-type inhibition. The inhibition action mechanism is discussed.
Abstract
CuCl2 обнаруживает неконкурентный тип ингибирования, в то вермя как тирозиновый и лизиновый комплексы меди характеризуются смешанным типом ингибирования. Обсуждён механизм действия ингибиторов.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
A. I. Archakov: Microsomal Oxidation. Nauka, Moskva 1975.
R. W. Estabrook, A. Hildebrandt, V. Ullrich: Z. Physiol. Chem.,349, 1605 (1968).
H. W. Strobel, M. J. Coon: J. Biol. Chem.,246, 7826 (1971).
C. Richter, A. Azzi, A. Wendel: FEBS Lett.,64, 332 (1976).
A. A. Akhrem, C. B. Bokut, D. I. Metelitsa: Dokl., Akad. Nauk BSSR,21, 637 (1977).
A. A. Akhrem, S. A. Usanov, S. S. Dvornikov, D. I. Metelitsa: Dokl. Akad. Nauk BSSR,223, 1014 (1975).
A. A. Akhrem, S. A. Usanov, D. I. Metelitsa: Dokl. Akad. Nauk BSSR,218, 1457 (1974).
A. J. Jornall, C. J. Berdwell, M. H. David: J. Biol. Chem.,177, 751 (1949).
T. Nash: Biochem J.,55, 416 (1953).
H. Kuthan, H. Tsajr, H. Graf, V. Ullrich, J. Werringloer, R. W. Estabrook: FEBS Lett.,91, 343 (1978).
A. A. Akhrem, S. M. Belskii, D. I. Metelitsa: Izv. Akad. Nauk BSSR, Ser. Khim. Nauk.,1, 87 (1978).
H. A. Sasame, J. R. Mitchell, J. R. Jillette: Fed. Proc.,34, 729 (1975).
P. Debey, C. Balney, P. Douzon: FEBS Lett.,69, 231 (1976).
C. Balney, P. Debey, P. Douzon: FEBS Lett.,69, 236 (1976).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kurchenko, V.P., Usanov, S.A. & Metelitsa, D.I. Inhibiting action of divalent copper compounds on microsomal oxidative demethylation of N,N-dimethylaniline. React Kinet Catal Lett 12, 31–37 (1979). https://doi.org/10.1007/BF02071421
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02071421