Abstract
A simple two step radiochemical separation scheme has been developed which permits the RNAA determination of As, Cd, Cu and Mo in biological matrices. The RNAA separation is applied following the INAA determination of at least 17 other elements in the same samples. Under our experimental conditions which included a four day decay period for handling and shipping from a remote reactor site, detection limits for As, Cd, Cu and Mo are 0.24, 6.6, 45 and 3.4 ng, respectively, in NBS biological standard reference materials SRM 1571 and 1567. Decontamination factors for the major spectral interferences,82Br,42K,24Na32P and122Sb have been determined and found to be sufficiently high for measurement of the elements of interest in most biological matrices. The overall INNA/RNAA procedure takes full advantage of high resolution Ge(Li) gamma-ray spectroscopy and involves minimal chemical processing.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Proc. Symp. Nuclear Activation Techniques in the Life Sciences, IAEA, Vienna, 1967.
Proc. Symp. Nuclear Activation Techniques in the Life Sciences, IAEA, Bled, Yugoslavia, 1972.
Proc. Symp. Nuclear Activation Techniques in the Life Sciences, IAEA, Vienna, 1978.
E. J. UNDERWOOD, Trace Elements in Human and Animal Nutrition, Academic Press, New York, 1977, p. 1.
WORLD HEALTH ORGANIZATION, W. H. O., Tech. Rep. Ser., 505, 1972.
V. VALKOVIC', Analysis of Biological Material for Trace Elements Using X-Ray Spectroscopy, CRC Press, Inc., Cleveland, Ohio, 1980, p. 91.
G. V. IYENGAR, W. E. KOLLMER, H. J. M. BOWEN, The Elemental Composition of Human Tissues and Body Fluids, Verlag Chemie, Weinheim/New York, 1978.
B. VENUGOPAL, T. D. LUCKEY, Metal Toxicity in Mammals-2, Plenum Press, New York, 1978, p. 209.
A. M. LEE, J. F. FRAUMENI, J. Nat. Cancer Inst., 42 (1969) 1045.
F. ROTH, Virchow Arch. Path. Anat., 331 (1958) 119.
E. G. JUNG, B. TRACHSEL, Arch. Klin. Exp. Derm., 237 (1970) 819.
G. H. MORRISON, Anal. Chem., 41 (1969) 1633; 44 (1972) 839.
E. S. GLADNEY, J. W. OWENS, Anal. Chem., 48 (1976) 2220.
E. S. GLADNEY, Anal. Letters, A11 (1978) 429.
M. GALLORINI, R. R. GREENBERG, T. E. GILLS, Anal. Chem., 50 (1978) 1479.
R. CALETKA, V. KRIVIN, Anal. Chim. Acta, 143 (1982) 269.
X. SUN, H. SU, S. GAO, L. SU, G. LIU, Nuclear Techniques (in Chinese), 4 (1982) 49.
Y. SUN, W. TIAN, J. XIAO, Y. ZHOU, Nuclear Techniques (in Chinese), 4 (1982) 28.
K. RENGAN, J. P. HAUSHALTER, J. D. JONES, J. Radioanal. Chem., 54 (1979) 347.
B. VENUGOPAL, T. D. LUCKEY, Metal Toxicity in Mammals-2, Plenum Press, New York, 1978, p. 79.
M. ANKE, A. HENNIG, H. J. SCHNEIDER, H. LUDKE, W. VON CAGERN, H. SCHLEGAL, In: Trace Element Metabolism in Animals, C. F. MILLS (Ed.), Livingstone, Edinburgh, 1970, p. 317.
G. E. CARTWRIGHT, In: Symposium on Copper Metabolism, W. D. McELROY, B. GLASS (Eds), Johns Hopkins Press, Baltimore, Maryland, 1950, p. 274.
B. VENUGOPAL, T. D. LUCKEY, Metal Toxicity in Mammals-2, Plenum Press, New York, 1978, p. 256.
W. D. EHMANN, W. R. MARKESBERY, T. I. M. HOSSAIN, M. ALAUDDIN, D. T. GOODIN, J. Radioanal. Chem., 70 (1982) 57.
R. A. NADKARNI, G. H. MORRISON, J. Radioanal. Chem., 43 (1978) 347.
L. A. CURRIE, Anal. Chem., 40 (1968) 587.
W. TIAN, W. D. EHMANN, J. Radioanal. Nucl. Chem, 84 (1984) 89.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tian, WZ., Ehmann, W.D. Radiochemical neutron activation analysis for arsenic, cadmium, copper and molybdenum in biological matrices. Journal of Radioanalytical and Nuclear Chemistry, Articles 89, 109–122 (1985). https://doi.org/10.1007/BF02070209
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02070209