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99mTc-Cu-citrate: A new complex for renal function studies

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Abstract

A method for preparing99mTc-citrate complex, using instantly formed cuprous ions for the reduction of pertechnetate is described. The labelling kinetics, formation rate and stability of99mTc-Cu-citrate complex were studied. Gel filtration using column scanning technique has been found to be a reliable and unique tool for determining the amount of99mTc-fractions as a function of time in the preparation. The kidney uptake and excretion characteristics suggest a potential usefulness of99mTc-Cu-citrate complex for renal function studies. The safety measures for the amount of the complex to be injected in man have been estimated.

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Authors and Affiliations

  1. Radioisotope Production Department, Nuclear Research Centre, Tuwaitha, Baghdad, (Iraq)

    A. M. Al-Hilli, N. H. Agha & S. Y. Al-Ani

Authors
  1. A. M. Al-Hilli
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  2. N. H. Agha
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  3. S. Y. Al-Ani
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Al-Hilli, A.M., Agha, N.H. & Al-Ani, S.Y. 99mTc-Cu-citrate: A new complex for renal function studies. Journal of Radioanalytical and Nuclear Chemistry, Articles 89, 55–62 (1985). https://doi.org/10.1007/BF02070203

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  • DOI: https://doi.org/10.1007/BF02070203

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