Journal of Assisted Reproduction and Genetics

, Volume 13, Issue 8, pp 684–685 | Cite as

Successful pregnancy in a familial mediterranean fever patient following assisted reproduction

  • Edward C. Ditkoff
  • Mark V. Sauer
Short Communications

Summary

We conclude that untreated women with FMF have up to a 30% incidence of infertility due to ovulatory dysfunction and peritoneal adhesions. Some of these women conceive during ovulation induction with or without insemination. We have described the first case of a successful and normal pregnancy in a patient with FMF following in vitro fertilization (IVF) while on prophylaxis colchicine therapy after other treatments for infertility were unsuccessful.

Keywords

Public Health Developmental Biology Infertility Colchicine Familial Mediterranean Fever 

References

  1. 1.
    Ehrenfeld M, Brzezinski A, Levy M, Eliakim M: Fertility and obstetric history in patients with patients with familial Mediterranean fever on long-term colchicine therapy. Br J of Obstet Gynaecol 1987;94:1186–1191Google Scholar
  2. 2.
    Gruberg L, Aksentijecvich I, Pras E, Kastner DL, Pras M: Mapping of the familial Mediterranean fever gene to chromosome 16. Am J Reprod Immun 1992;28(3–4):241–242Google Scholar
  3. 3.
    Mordel N, Birkenfeld A, Rubinger D, Schenker JG, Sadovsky E: Successful full-term pregnancy in Familial Mediterranean fever complicatied with amyloidosis: Case report and review of the literature. Fetal Diagn Ther 1993;8:129–134PubMedGoogle Scholar
  4. 4.
    Dickey RP, Gasser R, Olar TT, Taylor SN, Curole DN, Rye PH, Matulich EM: Relationship of initial chorionic sac diameter to abortion and abortus karyotype based on new growth curves for the 16th to 49th post-ovulation day. Hum Reprod 1994;9(3):559–565PubMedGoogle Scholar
  5. 5.
    Bromley B, Harlow BL, Laboda LA, Benacerraf BR: Small sac size in the first trimester: A predictor of poor fetal outcome. Radiology 1991;178(2):375–377PubMedGoogle Scholar
  6. 6.
    Zemer D, Livneh A, Pras M, Sohar E: Familial Mediterranean fever in the colchicine era: The fate of one family. Am J Med Genet 1993;45:340–344PubMedGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • Edward C. Ditkoff
    • 1
  • Mark V. Sauer
    • 1
  1. 1.Department of Obstetrics and Gynecology Division of Reproductive Endocrinology Columbia-Presbyterian Medical CenterColumbia UniversityNew York

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