Isolated teratozoospermia and in vitro fertilization
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Purpose: To show whether increased amounts of spermatozoa used in insemination of preovulatory oocytes in isolated teratozoospermia according to Kruger's strict criteria gives good fertilization rates.
Methods: This study was carried out from September 1993 to November 1994 for a total of 77 cycles, with sperm samples classified according to Kruger's strict classification. Group 1 (C; control) included 37 couples with normal sperm morphology (>14% normal; SC). Group 2 (GP; good prognosis) included 18 couples (morphology, ≥4 and ≤14% normal) and group 3 (T; teratozoospermic) included 11 couples, with isolated teratozoospermia in the male partner (morphology, <4% normal).
Results: No statistically significant difference was seen in the three groups regarding age, duration of infertility, aspirated follicles, oocytes collected, and embryos transferred. There is a statistically significantly difference (P<0.001) in the number of spermatozoa used in insemination in group 3.
Conclusions: In conclusion, a morphological classification using strict criteria in the assessment of sperm morphology is still very important, as increasing the sperm number of spermatozoa inseminated per oocyte may improve zona pellucida binding and give better IVF results.
Key wordshuman in vitro fertilization pregnancy strict morphology teratozoospermia
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