Digestive Diseases and Sciences

, Volume 40, Issue 6, pp 1395–1399 | Cite as

Severe thrombotic complications in a postpartum patient with active crohn's disease resulting in ischemic spinal cord injury

  • Warner Bruins Slot
  • Viviane van Kasteel
  • Emile G. Coerkamp
  • P. J. Seelen
  • Sjoerd D. J. van der Werf
Case Report


This report describes a 33-year-old female patient who presented with severe neurological symptoms and signs during postpartum relapse of Crohn's ileocolitis. The cause of the neurological deficit was extensive major vessel thrombosis resulting in spinal cord ischemia. Etiologic factors involved in this exceptional thrombotic state are discussed with emphasis on the relationship between low levels of folic acid, homocysteine metabolism, and coagulation.

Key words

thrombosis Crohn's disease spinal cord ischemia 


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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • Warner Bruins Slot
    • 1
  • Viviane van Kasteel
    • 1
  • Emile G. Coerkamp
    • 1
  • P. J. Seelen
    • 1
  • Sjoerd D. J. van der Werf
    • 1
  1. 1.From the Departments of Medicine, Neurology, and Diagnostic Radiology and Westeinde LaboratoriesWesteinde HospitalThe HagueThe Netherlands

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