Digestive Diseases and Sciences

, Volume 40, Issue 6, pp 1257–1260 | Cite as

FatalVibrio parahemolyticus septicemia in a patient with cirrhosis

A case report and review of the literature
  • Robert J. Hally
  • Raymond A. Rubin
  • Henry S. Fraimow
  • Margaret L. Hoffman-Terry
Case Report


Vibrio parahemolyticus has been well documented to cause outbreaks of infectious diarrhea, usually related to poor food handling; only rarely has it been reported to cause fatal septicemia. In contrast,Vibrio vulnificus is a well-known cause of septicemia, especially in patients with cirrhosis. A 31-year-old woman with cirrhosis who developed fatalV. parahemolyticus sepsis after ingesting raw seafood is described. We review the clinical syndromes associated with sepsis caused by these two organisms. Leg pain and bullous skin lesions may be a clue to the diagnosis. Febrile patients with cirrhosis should be questioned regarding recent seafood ingestion, and appropriate antibiotics chosen if this history is obtained. Physicians should inform patients at risk to avoid raw seafood in an attempt to prevent this potentially lethal syndrome.

Key words

cirrhosis Vibrio parahemolyticus Vibrio vulnificus septicemia 


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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • Robert J. Hally
    • 1
    • 2
  • Raymond A. Rubin
    • 1
    • 2
  • Henry S. Fraimow
    • 1
    • 2
  • Margaret L. Hoffman-Terry
    • 1
    • 2
  1. 1.From the Division of Gastroenterology, Department of MedicineThomas Jefferson University HospitalPhiladelphia
  2. 2.Division of Infectious Diseases, Department of MedicineThomas Jefferson University HospitalPhiladelphia

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