Abstract
A two-year endoscopic follow-up study of 45 gastric ulcer patients was conducted in order to ascertain the relationship betweenHelicobacter pylori infection, the transformation of ulcer scar patterns, and ulcer relapse during maintenance therapy. Endoscopic findings of gastric ulcer scar patterns, which established the quality of ulcer scars, were classified as follows: Sa, with a central depression, Sb, with a coarse regenerating mucosal pattern up to the center, and Sc, with a fine pattern. The proportion of ulcer relapses was 62% among 29H. pylori-positive patients and 0% among 16H. pylori-negative patients. In regard to the relationship betweenH. pylori infection and scar patterns, 94% of theH. pylori-negative patients displayed Sc scar patterns, while all theH. pylori-positive patients showed various scar patterns, ie, Sa in 38%, Sb in 28%, and Sc in 10%. Ulcer relapses in theH. pylori-positive cases were limited to the Sa and Sb groups (100% and 88%, respectively). In conclusion, our results indicate thatH. pylori infection plays an important role in the transformation of the ulcer scar patterns which relate to ulcer relapse.
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Sakaki, N., Momma, K., Yamada, Y. et al. An endoscopic study on relationship betweenHelicobacter pylori infection and endoscopic gastric ulcer scars. Digest Dis Sci 40, 1087–1092 (1995). https://doi.org/10.1007/BF02064204
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DOI: https://doi.org/10.1007/BF02064204