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Specific absorption parameters for uranium octoxide and dioxide applicable to the ICRP Publication 66 respiratory tract model

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Abstract

Literature data from in vivo chest measurements and urinary excretion rates of individuals exposed to U3O8 and UO2 were used to compare the results predicted by different models with empirical observations in humans. As a result the use of the respiratory tract model proposed in ICRP Publication 66 with its default absorption parameters underestimates urinary excretion of inhaled U3O8 and UO2. The new respiratory tract model also overpredicts the Fecal/Urine activity ratio, independently of the systemic model. For U3O8 and UO2 the choice of systemic model has very little influence on the predicted urinary excretion of inhaled compounds. On the other way, the choice of the respiratory tract model does influence the predicted urinary excretion significantly. In this work specific absorption parameters for U3O8 and UO2 were derived to be used in the respiratory tract model proposed in ICRP Publication 66. The predicted biokinetics of these compounds were compared with those derived for Type M and Type S compounds of uranium.

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References

  1. International Commission on Radiological Protection, Human Respiratory Tract Model for Radiological Protection, Report of a Task Group of the International Commission on Radiological Protection, ICRP Publication 66, Pergamon Press, 1994.

  2. International Commission on Radiological Protection, Limits for Intakes of Radionuclides by Workers, ICRP Publication 30, Pergamon Press, 1979.

  3. E. Ansoborlo, M. H. Henge-Napoli, M. Donnadieu-Claraz, M. Roy, P. Pihet, Radiat. Prot. Dosim., 53, 167 (1994) 163.

    Google Scholar 

  4. International Commission on Radiological Protection. Age-dependent doses to members of the public from intake of radionuclides: Part 3, Ingestion Dose Coefficients; ICRP Publication 69, Elsevier Science Ltd., Oxford, 1995.

    Google Scholar 

  5. M. E. Wrenn, L. Bertelli, P. W. Durbin, N. P. Singh, J. L. Lipsziein, K. F. Eckerman, Radiat. Prot. Dosim., 53 (1994) 255.

    Google Scholar 

  6. L. Bertelli, J. L. Lipsztein, Radiat. Prot. Dosim., 18 (1987) 209.

    Google Scholar 

  7. L. Bertelli, M. C. Lourenco, C. A. N. Oliveira, J. L. Lipsztein, An analytical mathematical method to calculate activity in body organs and excreta, Proc. Intem. Seminar of Application of Computer Technology to Radiation Protection, IAEA, Bled, Yugoslavia, 22–26 June 1987, Jozef Stefan Institute, 1989.

  8. L. Bertelli, M. E. Wrenn, Radiat. Prot. Dosim., 53 (1994) 277.

    Google Scholar 

  9. M. R. Avadhanula, R. M. Chatterjee, G. J. Healey, F. J. Horvath, M. P. Measures, H. Stocker, C. Pomroy, J. R. Johnson, D. W. Dunford, Canadian uranium fuel fabrication study: I. intake, retention and excretion monitoring results, II. comparison of results with metabolic models, Intern. Symp. on the Assessment of Radioactive Contamination in Man, International Atomic Energy Agency, IAEA-SM-276/51, 1985.

  10. M. R. Quastel, H. Taniguchi, T. R. Overton, J. D. Abbatt, Health Phys., 18 (1970) 233.

    PubMed  Google Scholar 

  11. H. Schieferdecker, H. Dilger, H. Doerfel, W. Rudolph, R. Anton, Health Phys., 48 (1985) 29.

    PubMed  Google Scholar 

  12. K. S. Thind, Health Phys., 53 (1987) 59

    PubMed  Google Scholar 

  13. BMDP Statistical Software, Dixon W. J., Berkeley-Los Angeles-Oxford, University of California Press, 1992.

    Google Scholar 

  14. D. R. Fisher, P. O. Jackson, G. G. Brodaczynski, R. I. Scherpelz, Health Phys., 45 (1983) 617.

    PubMed  Google Scholar 

  15. M. E. Wrenn, H. Ruth, D. Burleigh, N. P. Singh, J. Radioanal. Nucl. Chem., 156 (1992) 407.

    Google Scholar 

  16. M. E. D. Bains, P. W. J. Rowbury, Health Phys., 16 (1969) 449.

    PubMed  Google Scholar 

  17. N. B. Schultz, Inhalation cases of enriched insoluble uranium oxides, Proc. 1st Intern. Congress of Radiation Protection, Pt. 2,W. S. Snyder, et al. (Eds), Pergamon Press, Oxford, 1968.

    Google Scholar 

  18. E. Ansoborlo, P. Berard, J. Chalabreysse, Radiat. Prot. Dosim., 26 (1989) 101.

    Google Scholar 

  19. C. M. West, L. M. Scott, Health Phys., 12 (1966) 1545.

    PubMed  Google Scholar 

  20. J. Chalabreysse, P. Beau, C. Chevalier, L. Jeanmaire, G. Bataller, P. Berard, B. Gibert, Radiat. Prot. Dosim., 26 (1989) 49.

    Google Scholar 

  21. International Commission on Radiological Protection. Dose Coefficients for Intakes of Radionuclides by Workers, ICRP Publication 68, Elsevier Science Ltd., Oxford, 1994.

    Google Scholar 

  22. G. N. Stradling, J. C. Moody, J. Radioanal. Nucl. Chem., 197 (1995) 309.

    Google Scholar 

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Authors and Affiliations

  1. Institute of Radiation Protection and Dosimetry, National Nuclear Energy Commission, Av. Salvador Allende s/n, Cx. Postal 37750, CEP 22780-160, Rio de Janeiro, RJ, Brazil

    L. Bertelli & J. L. Lipsztein

  2. Institute of Nuclear Sciences and Alternative Energies, Santafe de Bogota D. C., Colombia

    A. Puerta

  3. Radiation Surveillance Associates, 1230 Princeton Ave., Salt Lake City, Utah, USA

    M. E. Wrenn

Authors
  1. L. Bertelli
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  2. A. Puerta
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  3. M. E. Wrenn
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  4. J. L. Lipsztein
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Bertelli, L., Puerta, A., Wrenn, M.E. et al. Specific absorption parameters for uranium octoxide and dioxide applicable to the ICRP Publication 66 respiratory tract model. J Radioanal Nucl Chem 226, 233–239 (1997). https://doi.org/10.1007/BF02063654

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  • DOI: https://doi.org/10.1007/BF02063654

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