Antonie van Leeuwenhoek

, Volume 15, Issue 1, pp 162–166 | Cite as

Antibody response against strains of influenza-A virus in ferrets with basic immunity

  • J. Mulder
  • J. van der Veen
  • L. M. Brans
  • S. W. Enserink
Article

Summary

In Holland ferrets are offered for sale with basic antibodies against one or more sub-groups of strains of influenza-A virus. With the haemagglutination inhibition test low basic antibody titers can only be detected by neutralising the non-specific inhibitor in the ferret sera. When such a ferret is infected with a strain of a heterologous sub-group, a considerable rise in antibodies is obtained against the homologous and heterologous sub-groups. It is very probable that the same holds for human beings. Some examples are given of haemagglutination-inhibition tests with serum pairs from adults who suffered from influenza in the epidemic of the winter of 1949 in Holland from which the non-specific inhibitor had been eliminated.

Keywords

Influenza Antibody Response Antibody Titer Inhibition Test Haemagglutination Inhibition 

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References

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Copyright information

© Swets en Zeitlinger 1949

Authors and Affiliations

  • J. Mulder
    • 1
  • J. van der Veen
    • 1
  • L. M. Brans
    • 1
  • S. W. Enserink
    • 1
  1. 1.Virus Laboratory of the University Medical ClinicLeyden

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