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Labelling of long chain fatty acids by non isotopic nucleophilic halogen exchange

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Abstract

The parameters of two exchange methods of preparing pure 97% labelled 17-Br-HDA in acetone and in benzene with dry NaI* in a closed system are described. In aprotic solvents the need for a phase transfer catalyst up to 50μg is necessary to dissolve the dry NaI*. The use of aqueous medium in the exchange is totally prohibited. Energies of activation are calculated for both reactions.

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Authors and Affiliations

  1. Chemistry Department, College of Science, King Saud University, Riyadh

    E. Hallaba, A. A. Al-Suhybani & F. S. Zaki

Authors
  1. E. Hallaba
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  2. A. A. Al-Suhybani
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  3. F. S. Zaki
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Hallaba, E., Al-Suhybani, A.A. & Zaki, F.S. Labelling of long chain fatty acids by non isotopic nucleophilic halogen exchange. Journal of Radioanalytical and Nuclear Chemistry, Articles 90, 225–231 (1985). https://doi.org/10.1007/BF02060776

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  • DOI: https://doi.org/10.1007/BF02060776

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