Abstract
PURPOSE: A case of a patient with familial adenomatous polyposis (FAP) is reported, in whom adenomas developed in an ileal pelvic pouch six years after it was made. This case is reported to serve as a warning that restorative proctocolectomy, a relatively recent addition to surgical options for FAP, does not remove the risk of metachronous intestinal neoplasia; it merely defers it. METHODS: Case of a patient with pouch polyposis was reviewed, and patient was prospectively studied after three months of sulindac therapy. RESULTS: Polyps not removed at first examination became much less prominent. Literature review reveals only one study of adenomas in pelvic pouches, with 7 cases of 38. CONCLUSION: Proctocolectomy and ileal pouch-anal anastomosis does not cure FAP, and multiple polyps can occur in the ileal pouch.
Similar content being viewed by others
References
Groden J, Thilveris A, Samowitz W,et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 1991;66:589–600.
Church JM, McGannon E, Hull-Boiner S,et al. Gastroduodenal polyps in patients with familial adenomatous polyposis. Dis Colon Rectum 1992;35:1170–3.
Ross JE, Mara JE. Small bowel polyps and carcinoma in intestinal polyposis. Arch Surg 1974;108:736–8.
Ambroze WL Jr, Dozois RR, Pemberton JH, Beart RW Jr, Ilstrup DM. Familial adenomatous polyposis: results following ileal pouch-anal anastomosis and ileorectostomy. Dis Colon Rectum 1992;35:12–5.
Johnson JA 3d, Talton DS, Poole GV. Adenocarcinoma of a Brooke ileostomy for adenomatous polyposis coli. Am J Gastroenterol 1993;88:1122–4.
Beart RW Jr, Fleming CR, Banks PM. Tubulovillous adenomas in a continent ileostomy after proctocoloectomy for familial polyposis. Dig Dis Sci 1982;27:553–6.
Nugent KP, Spigelman AD, Nicholls RJ, Talbot IC, Neale K, Phillips RK. Pouch adenomas in patients with familial adenomatous polyposis. Br J Surg 1993;80:1620.
Author information
Authors and Affiliations
About this article
Cite this article
Church, J.M., Oakley, J.R. & Wu, J.S. Pouch polyposis after ileal pouch-anal anastomosis for familial adenomatous polyposis. Dis Colon Rectum 39, 584–586 (1996). https://doi.org/10.1007/BF02058717
Issue Date:
DOI: https://doi.org/10.1007/BF02058717