Summary
The clinical and immunological follow-up of a 38-year-old female patient with hypereosinophilic syndrome and classical cardiac involvement, but without demonstrable degranulation of eosinophils and lacking binding of a specific antibody for activated eosinophils, is presented. Instead, the patient demonstrated all the immunological features of autoreactive myocarditis: cytolytic, complement-fixing antimyolemmal antibodies and increased concentrations of circulating immune complexes were present over 3 years.
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Supported by grants from the Deutsche Forschungsgemeinschaft (Ma 780/1-6).
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Maisch, B., Drude, L. & Kochsiek, K. Immunological features in a case of hypereosinophilic syndrome and myocarditis. Heart Vessels 5, 237–242 (1990). https://doi.org/10.1007/BF02058696
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DOI: https://doi.org/10.1007/BF02058696