Skip to main content

Left ventricular characteristics during exercise in patients after Fontan's operation for tricuspid atresia

Summary

Left ventricular function during supine bicycle exercise was studied using multigated blood pool imaging in ten patients with tricuspid atresia after Fontan's operation and in 13 children and adults (control group). The mean age of the patients was 16 years and the mean interval between operation and study was 5 years. The peak work loads that the patients could perform were similar to those in the control group. Work loads and heart rates during radionuclide study in the operated group were also similar to those in the control group. The left ventricular ejection fraction at rest and during exercise in the operated group was less than in the control group, although the net increase during exercise was similar in the two groups. During exercise, left ventricular end-diastolic volume decreased significantly in the operated group. In the control group, this variable did not change significantly. Left ventricular stroke volume increased during exercise in the control group but it did not change significantly in the operated group. These data indicate that in patients after Fontan's operation, left ventricular performance remains low during exercise, which is in part due to diminished left ventricular preload reserve, and this in turn may be caused by reduced reserve of right heart output.

This is a preview of subscription content, access via your institution.

References

  1. Nakae S, Imai Y, Harada Y, Sawatani K, Kawada M, Takanashi Y, Ishihara K, Hashimoto A, Koyanagi H, Kanaya M, Nakazawa M, Takao A (1985) Assessment of left ventricular function before and after Fontan's operation for the correction of tricuspid atresia. Heart Vessels 1: 83–88

    PubMed  Google Scholar 

  2. Nakazawa M, Nakanishi T, Okuda H, Satomi G, Nakae S, Imai Y, Takao A (1984) Dynamics of right heart flow in patients after Fontan procedure. Circulation 69: 306–312

    PubMed  Google Scholar 

  3. Behrendt DM, Rosenthal A (1980) Cardiovascular status after repair by Fontan procedure. Ann Thorac Surg 29: 322–330

    PubMed  Google Scholar 

  4. Stanton RE, Lurie PR, Lindesmith GG, Meyer BW (1981) The Fontan procedure for tricuspid atresia. Circulation 64 (Suppl II): 140–146

    Google Scholar 

  5. Ben Schachar G, Fuhrman BP, Wang Y, Lucas RV, Lock JE (1982) Rest and exercise hemodynamics after the Fontan procedure. Circulation 65: 1043–1048

    PubMed  Google Scholar 

  6. Kawasaki T, Kosaki F, Okawa S (1974) A new infantile acute febrile mucocutaneous lymph node syndrome prevailing in Japan. Pediatrics 54: 271–276

    PubMed  Google Scholar 

  7. Nakanishi T, Takao A, Nakazawa M, Endo M, Niwa K, Takahashi Y (1985) Mucocutaneous lymph node syndrome: clinical, hemodynamic, and angiographic features of coronary obstructive disease. Am J Cardiol 55: 662–668

    PubMed  Google Scholar 

  8. Paval DG, Zimmer OAM, Patterson VN (1977) In vivo labelling of red blood cells with99Tc. J Nuc Med 18: 305–308

    Google Scholar 

  9. Hiroe M, Sekiguchi M, Take M, Kusakabe K, Shigeta A, Hirosawa K (1985) Long follow-up study in patients with prior myocarditis by radionuclide methods. In: Sekiguchi M, Olson EGJ, Goodwin JF (eds) Myocarditis and related disorders. Springer, New York, pp 199–203

    Google Scholar 

  10. Bacharach SL, Green MV, Borer JS (1977) ECG-gated scintillation probe measurements of left ventricular function. J Nuc Med 18: 1176–1183

    Google Scholar 

  11. Snedecor GW, Cochron WF (1967) Statistical methods. Iowa State University Press

  12. Graham TP Jr, Franklin RCG, Wyse RKH, Gooch V, Deanfield JE (1986) Left ventricular wall stress and contractile function in childhood: normal values and comparison of Fontan repair versus palliation only in patients with tricuspid atresia. Circulation 74 (Suppl I): I-61–69

    Google Scholar 

  13. Hurwitz RA, Caldwell RL, Girod DA, Wellman H (1986) Left ventricular function in tricuspid atresia: a radionuclide study. J Am Coll Cardiol 8: 916–921

    PubMed  Google Scholar 

  14. Slutsky R, Karliner J, Ricci D, Schuller G, Pfistere M, Peterson K, Ashburn W (1979) Response of left ventricular volume to exercise in man assessed by radionuclide equilibrium angiography. Circulation 60: 565–571

    PubMed  Google Scholar 

  15. Benson L, Bonet J, McLaughlin P, Olley PM, Feiglin D, Druck M, Trusler G, Rowe RD, Morch J (1982) Assessment of right ventricular function during supine bicycle exercise after Mustard's operation. Circulation 65: 1052–1059

    PubMed  Google Scholar 

  16. Torso SD, Kelly MJ, Kalff V, Veneles AW (1985) Radionuclide assessment of left ventricular contraction at rest and during exercise following the Fontan procedure for either tricuspid atresia or single ventricle. Am J Cardiol 55: 1127–1132

    PubMed  Google Scholar 

  17. Sorensen SG, Ritchie JL, Caldwell JH, Hamilton GW, Kennedy JW (1980) Serial exercise radionuclide angiography. Circulation 61: 600–609

    PubMed  Google Scholar 

  18. Poliner LR, Dehmer GJ, Lewis SE, Parkey RW, Blomqvist GC, Willerson JT (1980) Left ventricular performance in normal subjects: a comparison of the responses to exercise in the upright and supine positions. Circulation 62: 528–534

    PubMed  Google Scholar 

  19. Dehmer GJ, Lewis SE, Hillis LD, Corbett J, Parkey RW, Willerson JT (1981) Exercise induced alterations in left ventricular volumes and the pressure-volume relationships. Circulation 63: 1008–1018

    PubMed  Google Scholar 

  20. Bar-Shlomo B, Druck M, Morch JE, Jabonsky G, Hilton D, Feiglin HI, McLaughlin PR (1982) Left ventricular function in trained and untrained healthy subjects. Circulation 65: 484–488

    PubMed  Google Scholar 

  21. Parrish MD, Boucek RJ, Burger J, Artman MF, Partain CL, Graham TP Jr (1985) Exercise radionuclide ventriculography in children: normal values for exercise variables and right and left ventricular function. Br Heart J 54: 509–516

    PubMed  Google Scholar 

  22. Laks H, Milliken JC, Perloff JK, Hellenbrand WE, George BL, Chin A, DiSessa TG, Williams RG (1984) Experience with the Fontan procedure. J Thorac Cardiovasc Surg 88: 939–951

    PubMed  Google Scholar 

Download references

Author information

Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Kondoh, C., Hiroe, M., Nakanishi, T. et al. Left ventricular characteristics during exercise in patients after Fontan's operation for tricuspid atresia. Heart Vessels 4, 34–39 (1988). https://doi.org/10.1007/BF02058685

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02058685

Key words

  • Tricuspid atresia
  • Fontan's operation
  • Exercise
  • Left ventricular function