Abstract
PURPOSE: This report presents a patient who developed signs and symptoms of acute appendicitis because of sarcoid involvement of the appendix. METHODS: This is a retrospective case review with review of the English language literature. RESULTS: The patient underwent appendectomy for suspected acute appendicitis. Histologically the appendix had no signs of acute inflammation but did have noncaseating granulomas. The patient's abdominal pain resolved following appendectomy, and she has had no further similar pain in the two years since the operation. CONCLUSION: Patients with sarcoidosis may develop signs and symptoms of acute appendicitis without inflammation. Operative exploration should not be delayed in equivocal cases of right lower quadrant abdominal pain in patients with sarcoidosis.
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References
Bascom R, Johns CJ. The natural history and management of sarcoidosis. Adv Intern Med 1986;31:213–41.
Fanburg BL. Sarcoidosis. In: Wyngaarden JB, Smith LH, Bennett JC, eds. Cecil textbook of medicine. 19th ed. Philadelphia: WB Saunders, 1992:430–5.
Fanburg BL. Sarcoidosis and other granulomatous diseases of the lung. New York: Marcel Dekker, 1983.
Johns CJ, Schonfeld SA, Scott PP. Proceedings of the tenth international conference on sarcoidosis and other granulomatous disorders. September 17–22, 1984. Ann N Y Acad Sci 1986:465.
Clarke H, Pollett W, Chittal S. Sarcoidosis with involvement of the appendix. Arch Intern Med 1983;142:1603–4.
Shienfeld WT, Rubinow M. Noncaseating epitheloid granuloma of the appendix (localized sarcoid disease?). J Int Coll Surg 1964;42:1–4.
Macleod IB, Jenkins AM, Gill W. Sarcoidosis involving the vermiform appendix. J R Coll Surg Edinb 1965;10:319–23.
Munt PW. Sarcoidosis of appendix presenting as appendiceal perforation and abscess. Chest 1974;66:295–7.
Bystrom J. Localized sarcoidosis of the appendix simulating Mb Crohn. Acta Chir Scand 1968;134:163–5.
Tinker MA, Viswanathan B, Laufer H, Margolis IB. Acute appendicitis and pernicious anemia as complications of gastrointestinal sarcoidosis. Am J Gastroenterol 1984;79:868–72.
McPherson JG, Yeoh CB. Rare manifestations of sarcoidosis. J Natl Med Assoc 1993;85:869–72.
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Cullinane, D.C., Schultz, S.C., Zellos, L. et al. Sarcoidosis manifesting as acute appendicitis. Dis Colon Rectum 40, 109–111 (1997). https://doi.org/10.1007/BF02055692
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DOI: https://doi.org/10.1007/BF02055692