Is colonic electrical activity a similar phenomena to small-bowel electrical activity?

Abstract

PURPOSE: This study was designed to investigate colonic spike bursts regarding 1) their migration behavior, 2) their pressure correlates, and 3) comparing colonic short spike bursts with spike bursts from migrating myoelectric complex from the small bowel. METHODS: Rectosigmoid electromyography and manometry were recorded simultaneously in seven normal volunteers and electromyography alone in five others during two hours of fasting and for two hours after one 2,100-kJ meal. One patient with an ileostomy was also studied by the same method to record the migrating myoelectric complex from the terminal ileum during fasting. RESULTS: Three kinds of spike bursts were observed in the pelvic colon: rhythmic short spike bursts, migrating long spike bursts, and nonmigrating long spike bursts. The meal significantly increased the number of migrating and nonmigrating long spike bursts (from 25 to 38.7 percent of the recording time; P <0.01). These bursts of potentials showed a peak 15 minutes after the meal, which may be caused by the gastrocolic reflex. Migrating long spike bursts started anywhere along the rectosigmoid and migrated from there aborad 82 percent of the time and orad or in both directions in 10 or 7 percent of the time, respectively. They originated pressure waves 99 percent of the time. Short spike bursts were more frequent before the meal (15.1 percent before and 9.6 percent after the meal), but the difference was not significant; they neither propagated nor initiated pressure waves detected by the miniballoon. CONCLUSIONS: Migrating long spike bursts were the only potentials that migrated, sometimes for short distances. Short spike bursts are a different phenomenon from the small-bowel migrating myoelectric complex because they do not migrate; they can occur during the postprandial period and never originated intraluminal pressure waves.

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References

  1. 1.

    Daniel EE, Berezin I. Interstitial cells of Cajal: are they major players in control of gastrointestinal motility? J Gastrointest Mot 1992;4:1–24.

    Google Scholar 

  2. 2.

    Tamai T, Prosser CL. Differentiation of slow potentials and spikes in longitudinal muscle of cat intestine. Am J Physiol 1966;210:452–8.

    PubMed  Google Scholar 

  3. 3.

    Kobayashi M, Prosser CL, Nagai T. Electrical properties of intestinal muscle as measured intracellularly and extracellularly. Am J Physiol 1967;213:275–86.

    PubMed  Google Scholar 

  4. 4.

    Szurszewski JH, Code CF. Activity fronts of the canine small intestine. Gastroenterology 1968;54:1304.

    Google Scholar 

  5. 5.

    Vantrappen G, Janssens J, Coremans G, Jian R. Gastrointestinal motility disorders. Dig Dis Sci 1986;31:5S-25S.

    PubMed  Google Scholar 

  6. 6.

    Christensen J, Anuras S, Arthur C. Influence of intrinsic nerves on electromyogram of cat colonin vitro. Am J Physiol 1978;3:E641–7.

    Google Scholar 

  7. 7.

    Sarna SK. Giant migrating contractions and their myoelectric correlates in the small intestine. Am J Physiol 1987;253:G697–705.

    PubMed  Google Scholar 

  8. 8.

    Christensen J, Anuras S, Hauser RL. Migrating spike bursts and electrical slow waves in the Cat colon: effect of sectioning. Gastroenterology 1974;66:240–7.

    PubMed  Google Scholar 

  9. 9.

    Bueno L, Fioramonti J, Ruckebusch Y, Frexino J, Coulom P. Evaluation of colonic myoelectrical activity in health and functional disorders. Gut 1980;21:480–5.

    PubMed  Google Scholar 

  10. 10.

    Schang JC, Devroede G. Fasting and posprandial myoelectric spiking activity in the human sigmoid colon. Gastroenterology 1983;85:1048–53.

    PubMed  Google Scholar 

  11. 11.

    Huizinga JD, Daniel EE. Control of human colonic motor function. Dig Dis Sci 1986;31:864–77.

    Google Scholar 

  12. 12.

    Sarna SK, Bardakjian BL, Waterfal WE, Lind JF. Human colonic electrical control activity (ECA). Gastroenterology 1980;78:1526–36.

    PubMed  Google Scholar 

  13. 13.

    Sarna SK, Waterfal WE, Bardakjian BL. Types of human colonic electrical activities recorded postoperatively. Gastroenterology 1981;81:61–70.

    PubMed  Google Scholar 

  14. 14.

    Dauchel J, Schang JC, Kachelhoffer J, Eloy RE, Grenier JF. Gastrointestinal myoelectric activity during the postoperative period in man. Digestion 1976;14:293–303.

    PubMed  Google Scholar 

  15. 15.

    Fleckenstein P. A probe for intraluminal recording of myoelectric activity from multiple sites in human small intestine. Scand J Gastroenterol 1978;13:767–70.

    PubMed  Google Scholar 

  16. 16.

    Fioramonti J, Bueno L, Frexinos J. Sonde endoluminale pour l'exploration electromyographique de la motricité colique chez l'homme. Gastroenterol Clin Biol 1980;4:546–50.

    PubMed  Google Scholar 

  17. 17.

    Bouvier M, Grimaud JC, Naudy B, Salducci J. Effects of morphine on electrical activity of the rectum in man. J Physiol 1987;388:153–61.

    PubMed  Google Scholar 

  18. 18.

    Wright SH, Snape WJ, Battle W, Cohen S, London RL. Effect of dietary components on gastrocolonic response. Am J Physiol 1980;238:G228–32.

    PubMed  Google Scholar 

  19. 19.

    Daniel EE, Chapman K. Electrical activity of the gastrointestinal tract as an indication of mechanical activity. Dig Dis Sci 1963;8:54–102.

    Google Scholar 

  20. 20.

    Connell AM. The motility of the pelvic colon. 1. Motility in normals and in patients with asymptomatic duodenal ulcer. Gut 1961;2:175–86.

    PubMed  Google Scholar 

  21. 21.

    Connell AM, Rowlands EN. Wireless telemetering from the digestive tract. Gut 1960;1:266–72.

    PubMed  Google Scholar 

  22. 22.

    Ritchie JA, Ardran GM, Truelove SC. Motor activity of the sigmoid colon of humans: a combined study by intraluminal pressure recording and cinerradiography. Gastroenterology 1962;43:642–68.

    PubMed  Google Scholar 

  23. 23.

    Sarna S, Latimer P, Campbell D, Waterfall WE. Electrical and contractile activities of the human rectosigmoid. Gut 1982;23:698–705.

    PubMed  Google Scholar 

  24. 24.

    Sarna SK. Myoelectric correlates of colonic motor complexes and contractile activity. Am J Physiol 1986;250:G213–20.

    PubMed  Google Scholar 

  25. 25.

    Medeiros JA, Pontes FA. Electromyography and manometry of the pelvic colon—a contribution to the understanding of it's function. Eur J Gastroenterol Hepatol 1996;8:453–9.

    PubMed  Google Scholar 

  26. 26.

    Bouvier M, Grimaud JC, Naudy B, Abysique A. Effects of stimulation of vesical afferents on colonic motility in cats. Gastroenterology 1990;98:1148–54.

    PubMed  Google Scholar 

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Correspondence to Dr. José A. S. Medeiros M.D., Ph.D..

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Supported by a grant from the Instituto Nacional de Investigação Científica, Proc. DBI-22086.

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Medeiros, J.A.S., Pontes, F.A. & Mesquita, O.A.R.O. Is colonic electrical activity a similar phenomena to small-bowel electrical activity?. Dis Colon Rectum 40, 93–99 (1997). https://doi.org/10.1007/BF02055689

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Key words

  • Smooth muscle
  • Electromyography
  • Intestinal motility
  • Motility
  • Electrophysiology