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Immunologic conditions and infectious complications in colon and rectal surgery for neoplasms

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Diseases of the Colon & Rectum

Abstract

The authors evaluated the peroperative immunologie state of patients with colorectal tumors and controlled the postoperative incidence of infections. Twenty-one patients were studied, and delayed type hypersensitivity reactivity determined by the CMI multitest (Merieux) eight days before and eight days after surgery. A lymphocytogram was performed using monoclonal antibodies. A significant percentage of patients were anergic preoperatively. Immunologic analysis revealed lymphocytosis in the first postoperative period. The largest absolute quantitative increase was shown by NK CD16 + cells. It is possible that the results, obtained by dynamic monitoring of the main parameters of cellular immunity, will offer a new way for prognostic evaluation of surgical risk.

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Read at the XIIth Biennial Congress of the International Society of University Colon and Rectal Surgeons, Glasgow, Scotland, July 10 to 14, 1988.

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Fragapane, P., Varvello, G., Bossotti, M. et al. Immunologic conditions and infectious complications in colon and rectal surgery for neoplasms. Dis Colon Rectum 33, 302–304 (1990). https://doi.org/10.1007/BF02055472

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  • DOI: https://doi.org/10.1007/BF02055472

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