Triamcinolone improves outcome in crohn's disease strictures
- 39 Downloads
PURPOSE: This study was undertaken to examine the effect of local injection of potent steroids on recurrence of Crohn's disease strictures. METHODS: Ten patients with colonic strictures attributable to Crohn's disease were treated by dilation and injection of triamcinolone. Five of them had postoperative strictures. RESULTS: Patients were followed for 1.5 to 3 years. Two patients required additional dilation and injection of steroids after one year. Eight patients remained well. CONCLUSION: Local injection of steroids improves outcome in strictures caused by Crohn's disease.
Key wordsCrohn's disease Colonic strictures Triamcinolone
Unable to display preview. Download preview PDF.
- 2.Ketchum LD, Smith J, Robinson DW, Masters FW. The treatment of hypertropic scar, keloid and scar contracture by triamcinolone acetonid. J Plast Reconstr Surg 1966;38:209–11.Google Scholar
- 3.Griffith BH. The treatment of keloids with triamcinolone acetonide. J Plast Reconstr Surg 1966;38:202–8.Google Scholar
- 9.Alexander-Williams J. Conservative nonresection operations for Crohn's disease. In: Najarian JS, Delaney JP, eds. Advances in gastrointestinal surgery. Chicago: Year Book Medical Publishers, 1984.Google Scholar
- 10.Rolney P, Blomberg B, Jarnerot G. Endoscopic treatment of anastomotic strictures in Crohn's disease [abstract]. Gastroenterology 1991;100:A244.Google Scholar
- 11.Greenberger NJ. Indications for surgery in inflammatory bowel disease: a gastroenterologist's opinion: In: Kirsner JB, ed. Inflammatory bowel disease. 3rd ed. Philadelphia: Lea & Febiger, 1988:565.Google Scholar
- 18.Ketchum LD, Robinson DW, Masters FW. The degradation of mature collagen: a laboratory study. J Plast Reconstr Surg 1967;40:89–91.Google Scholar