Summary
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1.
Three cases of glucose-6-phosphate dehydrogenase deficiency in red cells of patients with haemolytic anaemia are reported.
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2.
In one no extrinsic causal factor of haemolysis could be found.
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3.
A study of the dynamics of intracellular metabolism showed that the glucose-6-phosphate dehydrogenase reaction was less active in intact cells than normal and could not be effectively stimulated by methylene blue.
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4.
It was shown that cells with diminished reduced glutathione and containing Heinz bodies are rapidly removed from the circulation by liver and spleen on crosstransfusion.
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Bailey, I.S., de Loecker, W.C.J. & Prankerd, T.A.J. Glucose-6-phosphate dehydrogenase deficiency in red cells. Z. Gesamte Exp. Med. 134, 260–267 (1961). https://doi.org/10.1007/BF02054903
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DOI: https://doi.org/10.1007/BF02054903